Protein Alignment CG11034 and Dpp9

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001347213.1
• Gene: Dpp9 / 224897
• MGIID: 2443967
• Length: 921
• Species: Mus musculus
• Alignment Length: 708
• Identity: 166/708 - (23%)
• Similarity: 277/708 - (39%)
• Gaps: 202/708 - (28%)

  Fly   156 DRLAYVYLNN-----VFIHFSESLEISITDDGVDGVVYN----GVPDWVYEEEVLSSGSAIWW-- 209
            |...:.::||     ..|...|...::....|..||:.|    ||..:|.:|| ....:..||
Mouse   255 DPAFFSFINNSDLWVANIETGEERRLTFCHQGSAGVLDNPKSAGVATFVIQEE-FDRFTGCWWCP 318

  Fly   210 --SSDGS------RLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLK-----YPKSGSKNPV 261
              |.:||      |:.....:::|||..           ....|..|:.|     ||::|||||.
Mouse   319 TASWEGSEGLKTLRILYEEVDESEVEVI-----------HVPSPALEERKTDSYRYPRTGSKNPK 372

  Fly   262 VSLRVYDVSDNDPTMH----------TIVAPVDIVGD--DHILQSVVWSNSTHLLITWMNRRQN- 313
            ::|::.::.    |.|          .:|.|...:..  ::|.::....:..:....:::|.|.
Mouse   373 IALKLAELQ----TDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQR 433

  Fly   314 -----------LTSIQSCSYEGDCVEVKRL-----------------EEPQGWV---DISTP--- 344
                       :.:::|        |.:|.                 |....|:   ||..|
Mouse   434 LQLVLLPPALFIPAVES--------EAQRQAAARAVPKNVQPFVIYEEVTNVWINVHDIFHPFPQ 490

  Fly   345 ------KCLSTGKSCIFGYFIDNWHQVWNLDLETGLNSWQ--------------------SRGNF 383
                  .|......|..|:.  :.::| .::|:|....|.                    :.|.:
Mouse   491 AEGQQDFCFLRANECKTGFC--HLYRV-TVELKTKDYDWTEPLSPTEDEFKCPIKEEVALTSGEW 552

  Fly   384 TVLSVYG----YDEARDKLYYQATLPGDPSVYHVF--SNDECLSCGQIDADGAACRSASGTFSKS 442
            .|||.:|    .:|....:|:|.| ...|..:|::  |.:   |.|:|........|.|.:.|:|
Mouse   553 EVLSRHGSKIWVNEQTKLVYFQGT-KDTPLEHHLYVVSYE---SAGEIVRLTTLGFSHSCSMSQS 613

  Fly   443 F----SYY----TLSC------TGPNPS--------YTRIFEASTKTLQVDWEPNTAYRKQIEEK 485
            |    |:|    |..|      :||:..        :..:.||:  ....|:.|...:...
Mouse   614 FDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAA--NCPPDYVPPEIFHFH---- 672

  Fly   486 LRPSYRFMNVTLADGSIGYAKLALPPNFVETKKYPLIVVVYQGPNSVRVTNGF------------ 538
                      |.||..: |..:..|......:|:|.::.||.||....|.|.|
Mouse   673 ----------TRADVQL-YGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLA 726

  Fly   539 TLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAER 603
            :|||...|          |||||:..:|.....::.|.:|..|:|||:...:::.:...|:|..|
Mouse   727 SLGYAVVV----------IDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSR 781

  Fly   604 CGIWGWSYGGYMTAK-TIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNES 667
            ..|.||||||:::.. .|.|  .:||:..::.||||.|:.|||.||||||.:|  ::|.:.|...
Mouse   782 VAIHGWSYGGFLSLMGLIHK--PQVFKVAIAGAPVTVWMAYDTGYTERYMDVP--ENNQQGYEAG 842

  Fly   668 SVFGNLENF--KSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGI 723
            ||..::|..  :.:..|::||..|:|||:.|:..|...|.|....::.|.|.:|.|.|
Mouse   843 SVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSI 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	82/425 (19%)
		Peptidase_S9	538..745	CDD:459761	67/201 (33%)
Dpp9	NP_001347213.1	Dpp_8_9_N	<82..193	CDD:466112
		DPPIV_N	204..628	CDD:395744	79/403 (20%)
		Peptidase_S9	720..921	CDD:459761	66/195 (34%)