Protein Alignment CG11034 and Fap

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_620205.1
• Gene: Fap / 192203
• RGDID: 621253
• Length: 761
• Species: Rattus norvegicus
• Alignment Length: 800
• Identity: 259/800 - (32%)
• Similarity: 410/800 - (51%)
• Gaps: 107/800 - (13%)

  Fly     7 LITAFGL-------FITVC--PRPSTAAAVIGRVDGAEGNKTAWELT--EALYGTSGLRSFNGTW 60
            |.|.||:       .:.:|  .|||       ||...||| |...||  :.|.||...:::...|
  Rat     5 LKTVFGVTTLVALALVVICIVLRPS-------RVYSPEGN-TGRSLTLKDILNGTFSYKTYFPNW 61

  Fly    61 ITGTYY--TATDRSIHKFNAATKTDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFRHSY 123
            |:...|  .:.|.:|..:|..|:...|..::|.:.:.....:.||||...|.:..:.::.:|:||
  Rat    62 ISEQEYLHQSEDDNIVFYNIETRESYIILSNSTMKSVNATDYGLSPDRQFIYLESDYSKLWRYSY 126

  Fly   124 IAQYDVFDIETNTTVQIHK-GEKLQYCGWSPLRDRLAYVYLNNVFI-HFSESLEISITDDGVDGV 186
            .|.|.::|::....|:.:: ...:||..|||:..:|||||.||::: .........||..|.:..
  Rat   127 TATYYIYDLQNGEFVRGYELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITYTGRENR 191

  Fly   187 VYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLK 251
            ::||:||||||||:|::..|:|||.||..||...|||:::....|..||||     |||....:.
  Rat   192 IFNGIPDWVYEEEMLATKYALWWSPDGKYLAYVEFNDSDIPIIAYSYYGDG-----QYPRTINIP 251

  Fly   252 YPKSGSKNPVVSLRVYDVSDNDPTMHTI----VAPVD------IVGDDHILQSVVWSNSTHLLIT 306
            |||:|:|||:|.:.:.|         ||    |.|::      |...|:....:.|..:..:.:.
  Rat   252 YPKAGAKNPIVRVFIVD---------TIYPHHVGPIEVPVPEMIASSDYYFTWLTWVTNERVCLQ 307

  Fly   307 WMNRRQNLTSIQSCSYE-----GDCVE-VKRLEEPQ-GWVD---ISTPKCLSTGKSCIFGYFID- 360
            |:.|.||::.:..|.:.     .||.: .:.:||.: ||..   :||| ..|...:..:..|.|
  Rat   308 WLKRVQNVSVLSICDFREDWHAWDCPKNQEHIEESRTGWAGGFFVSTP-AFSQDAASYYKIFSDK 371

  Fly   361 ----NWHQVWN-----LDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQAT----LPGDPSVYH 412
                :.|.:.:     :.:.:|  .|:        ::|.:...:|.|:|.:.    .||..::|.
  Rat   372 DGYKHIHYIKDTVENAIQITSG--KWE--------AIYIFRVTQDSLFYSSNEFEGYPGRRNIYR 426

  Fly   413 VF-----SNDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEAST-KTLQVD 471
            :.     .:.:|::|   ......|:..:.:||....||.|.|.||....:.:.:..| :.:||
  Rat   427 ISIGNSPPSKKCVTC---HLRKERCQYYTASFSYKAKYYALICYGPGLPISTLHDGRTDQEIQV- 487

  Fly   472 WEPNTAYRKQIEEKLR----PSYRFMNVTLADGSIGY-AKLALPPNFVETKKYPLIVVVYQGPNS 531
            .|.|    |::|..||    |:.....  |.||.:.: .|:.|||.|..:|||||::.||.||.|
  Rat   488 LEEN----KELENALRNIQLPAVEIKK--LEDGGMTFWYKMILPPQFDRSKKYPLLIQVYGGPCS 546

  Fly   532 VRVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNL 596
            ..|.:.|::.:..::.:....:.|.:|||||..:|...|.:|...||.:||||||...|...: :
  Rat   547 QSVKSVFSVNWITYLASKEGIVVALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIE-M 610

  Fly   597 AFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNL 661
            .|:|..|..|||||||||:::..:..... :|:||::||||:||.||.:|||||:|||||.||||
  Rat   611 GFIDEGRIAIWGWSYGGYVSSLALASGTG-LFKCGIAVAPVSSWEYYASIYTERFMGLPTKDDNL 674

  Fly   662 KKYNESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGI--G 724
            :.|..|:|....|.|::.|:|||||:.|||||:|:|..:||.|....:.|:...|:|:||||  |
  Rat   675 EHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGISSG 739

  Fly   725 NALPHLYHTIDAFWTNCLNL 744
            .:..|||..:..|...|.:|
  Rat   740 RSQNHLYTHMTHFLKQCFSL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	110/394 (28%)
		Peptidase_S9	538..745	CDD:459761	90/208 (43%)
Fap	NP_620205.1	DPPIV_N	106..473	CDD:395744	110/394 (28%)
		Peptidase_S9	553..757	CDD:459761	89/205 (43%)