Protein Alignment CG11034 and Fap

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_032012.1
• Gene: Fap / 14089
• MGIID: 109608
• Length: 761
• Species: Mus musculus
• Alignment Length: 795
• Identity: 262/795 - (32%)
• Similarity: 411/795 - (51%)
• Gaps: 97/795 - (12%)

  Fly     7 LITAFGL-------FITVC--PRPSTAAAVIGRVDGAEGN-KTAWELTEALYGTSGLRSFNGTWI 61
            |.|.||:       .:.:|  .|||       ||...||| |.|..|.:.|.||...:::...||
Mouse     5 LKTVFGVTTLAALALVVICIVLRPS-------RVYKPEGNTKRALTLKDILNGTFSYKTYFPNWI 62

  Fly    62 TGTYY--TATDRSIHKFNAATKTDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFRHSYI 124
            :...|  .:.|.:|..:|..|:...|..::|.:.:.....:.||||...:.:..:.::.:|:||.
Mouse    63 SEQEYLHQSEDDNIVFYNIETRESYIILSNSTMKSVNATDYGLSPDRQFVYLESDYSKLWRYSYT 127

  Fly   125 AQYDVFDIETNTTVQIHK-GEKLQYCGWSPLRDRLAYVYLNNVFI-HFSESLEISITDDGVDGVV 187
            |.|.::|::....|:.:: ...:||..|||:..:|||||.||::: .........||..|.:..:
Mouse   128 ATYYIYDLQNGEFVRGYELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITYTGRENRI 192

  Fly   188 YNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLKY 252
            :||:||||||||:|::..|:|||.||..||...|||:::....|..||||     |||....:.|
Mouse   193 FNGIPDWVYEEEMLATKYALWWSPDGKFLAYVEFNDSDIPIIAYSYYGDG-----QYPRTINIPY 252

  Fly   253 PKSGSKNPVVSLRVYDVSDNDPTMHTIVAPVD------IVGDDHILQSVVWSNSTHLLITWMNRR 311
            ||:|:|||||  ||:.|   |.|....|.|::      |...|:....:.|.:|..:.:.|:.|.
Mouse   253 PKAGAKNPVV--RVFIV---DTTYPHHVGPMEVPVPEMIASSDYYFSWLTWVSSERVCLQWLKRV 312

  Fly   312 QNLTSIQSCSYEGD-----CVE-VKRLEEPQ-GWVD---ISTPKCLSTGKSCIFGYFID-----N 361
            ||::.:..|.:..|     |.: .:.:||.: ||..   :||| ..|...:..:..|.|     :
Mouse   313 QNVSVLSICDFREDWHAWECPKNQEHVEESRTGWAGGFFVSTP-AFSQDATSYYKIFSDKDGYKH 376

  Fly   362 WHQVWN-----LDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQAT----LPGDPSVYHVF--- 414
            .|.:.:     :.:.:|  .|:        ::|.:...:|.|:|.:.    .||..::|.:.
Mouse   377 IHYIKDTVENAIQITSG--KWE--------AIYIFRVTQDSLFYSSNEFEGYPGRRNIYRISIGN 431

  Fly   415 --SNDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEAST-KTLQVDWEPNT 476
              .:.:|::|   ......|:..:.:||....||.|.|.||....:.:.:..| :.:|| .|.|
Mouse   432 SPPSKKCVTC---HLRKERCQYYTASFSYKAKYYALVCYGPGLPISTLHDGRTDQEIQV-LEEN- 491

  Fly   477 AYRKQIEEKLR----PSYRFMNVTLADGSIGY-AKLALPPNFVETKKYPLIVVVYQGPNSVRVTN 536
               |::|..||    |......  |.||.:.: .|:.|||.|..:|||||::.||.||.|..|.:
Mouse   492 ---KELENSLRNIQLPKVEIKK--LKDGGLTFWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVKS 551

  Fly   537 GFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDA 601
            .|.:.:..::.:....:.|.:|||||..:|...|.:|...||.:||||||...|...: :.|:|.
Mouse   552 VFAVNWITYLASKEGIVIALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIE-MGFIDE 615

  Fly   602 ERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNE 666
            ||..|||||||||:::..:..... :|:||::||||:||.||.:||:||:|||||.||||:.|..
Mouse   616 ERIAIWGWSYGGYVSSLALASGTG-LFKCGIAVAPVSSWEYYASIYSERFMGLPTKDDNLEHYKN 679

  Fly   667 SSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGI--GNALPH 729
            |:|....|.|::.|:|||||:.|||||:|:|..:||.|....:.|:...|:|:||||  |.:..|
Mouse   680 STVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGISSGRSQNH 744

  Fly   730 LYHTIDAFWTNCLNL 744
            ||..:..|...|.:|
Mouse   745 LYTHMTHFLKQCFSL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	113/390 (29%)
		Peptidase_S9	538..745	CDD:459761	91/209 (44%)
Fap	NP_032012.1	DPPIV_N	106..473	CDD:395744	113/390 (29%)
		Peptidase_S9	553..757	CDD:459761	89/205 (43%)