DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11034 and LOC101886435

DIOPT Version :9

Sequence 1:	NP_001285638.1	Gene:	CG11034 / 33810	FlyBaseID:	FBgn0031741	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_009295302.1	Gene:	LOC101886435 / 101886435	-ID:	-	Length:	793	Species:	Danio rerio

Alignment Length:	732	Identity:	203/732 - (27%)
Similarity:	335/732 - (45%)	Gaps:	76/732 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 TWITGTYYTATDRSIHKF--NAATK-TDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFR 120
            ||::....:...:..|..  |.:|. |..:..||:.  :.....|.:|.|...||:.:|:...|.
Zfish    81 TWLSEHEVSLCTQEGHVLIHNLSTNLTTTLLDNSTL--DLKSMKFQVSADKRFILMAYNIQHVFS 143

  Fly   121 HSYIAQYDVFDIETNTTVQIHKGEK----LQYCGWSPLRDRLAYVYLNNVFIHFS-ESLEISITD 180
            .|:.|.:.::.:.:...|.:...|:    |||..|.|..::|.||:.|:::.... .|..:.:|.
Zfish   144 QSFTASFAIYIVSSGDIVDLTPSEEDTSVLQYAAWGPQGNQLVYVFENDIYYKPDVSSKAMRLTA 208

  Fly   181 DGVDGVVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQ-- 243
            .|..|:|.||:.||.||||:|....|.||:.||:|||             |....:.||.|.:
Zfish   209 SGRKGMVVNGLSDWTYEEEILLKYPAFWWAKDGARLA-------------YLSINNSATPFMEIH 260

  Fly   244 ------YPHEEQLKYPKSGSKNPVVSLRVYDVSDNDPTMHTI-VAPVDIVGD-DHILQSVVWSNS 300
                  ||......|||:||:.|..||.|.::..   ..||: :.|.|.... |..:..|.|.:|
Zfish   261 HFLGGSYPSNVLYPYPKAGSRIPSASLFVVNLYG---PAHTLEMFPPDSQNSRDSYISMVSWISS 322

  Fly   301 THLLITWMNRRQNLTSIQSC-SYEGDCVE-----------VKRLEEPQGWVDISTPKCLSTGKSC 353
            |.|.:.|:||.||.:.:..| :..|.|.|           .:|.|||....|.|....:...|..
Zfish   323 TRLTVRWLNRVQNQSVLCVCEATTGACSERHQMAMDFWHNNQRQEEPLFTADGSLFYLILPAKQG 387

  Fly   354 IFGYFIDNWHQVWNLDLETGLNSWQSR----GNFTVLSVYGYDEARDKLYYQATLPGDPSVYHVF 414
            ..|.|:    .:.:|..:....|...|    ||:.|:|:...||..||:|:.:......| .|::
Zfish   388 ARGEFL----HIASLPAQASSPSVSPRFLTSGNWDVISLCALDEENDKIYFLSAEESQQS-RHLY 447

  Fly   415 S-------NDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEASTKTLQVDW 472
            |       :.:||:|...:    .|......||.:.:|:||.|.||......|...|........
Zfish   448 SVELGGVFHRQCLTCNLFE----RCSFFRADFSPNQTYFTLYCLGPGVPKVTIHSTSDPFRYTVV 508

  Fly   473 EPNTAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETKKYPLIVVVYQGPNSVRVTNG 537
            |.|:.....:|.|..|...:..:: :|.|....|::|||.: |...:||::::...|....||..
Zfish   509 EDNSVLAMSLETKQLPETLYHTLS-SDNSDLDVKMSLPPGY-EGNLHPLLIIIDSIPGRPSVTEE 571

  Fly   538 FTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAE 602
            |.||:...:::......|:||.|...::.:.........||...::|:|.|..|:.: |.::||:
Zfish   572 FALGWPEVLSSMHGVALAWIDSRSRISQTQKSSTLDPRKLGSLRIKDKLGVVEWLMK-LPYIDAK 635

  Fly   603 RCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNES 667
            |..::|..:|||:..|.: ...|::|:|...:||:|.:..|...::||::|||..:::  .|..:
Zfish   636 RIAVYGKGFGGYLGLKML-TGTDQMFRCAAVMAPITDFKLYSAAFSERFLGLPAKEEH--SYMTA 697

  Fly   668 SVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGI--GNALPHL 730
            |:..::...|..:||||||:.|..||:|||..|...|.:.:..:..|.|.||.|.:  ..:..||
Zfish   698 SLLDDIHKLKDENFLLIHGTADARVHFQHSAELLSRLVKVEANYTLQLYPDEGHTLREERSQQHL 762

  Fly   731 YHTIDAFWTNCLNLDVY 747
            :.||..:..|||..|.:
Zfish   763 HRTILHYLHNCLKYDPF 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_001285638.1	DPPIV_N	103..457	CDD:279298	111/391 (28%)
CG11034	NP_001285638.1	Peptidase_S9	538..745	CDD:278741	63/208 (30%)
LOC101886435	XP_009295302.1	DPPIV_N	126..492	CDD:279298	111/390 (28%)
		DAP2	<428..775	CDD:224423	99/357 (28%)
		Abhydrolase	609..775	CDD:304388	55/169 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46052
OrthoDB	1	1.010	-	-		D269253at2759
OrthoFinder	1	1.000	-	-		FOG0000419
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100574
Panther	1	1.100	-	-	O	PTHR11731
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X274
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.930