DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9171 and large1

DIOPT Version :9

Sequence 1:	NP_001162891.1	Gene:	CG9171 / 33807	FlyBaseID:	FBgn0031738	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001004537.1	Gene:	large1 / 446213	ZFINID:	ZDB-GENE-061204-1	Length:	757	Species:	Danio rerio

Alignment Length:	419	Identity:	91/419 - (21%)
Similarity:	143/419 - (34%)	Gaps:	138/419 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 RSLINC-FDHDYHQQTLQRG-----------DFWVLQNYVRAEHGDIKCHESITYTTHADY-TFL 224
            |.|..| .:.|::.:.||:.           :|       |.|...:  |.:..|..|.:| ..:
Zfish   415 RELFGCPSETDHNSENLQKTLSELDEDDPCYEF-------RRERFTV--HRTHVYFLHYEYEPTV 470

  Fly   225 DN----------------LVPLLERWNAPVSIAMHAPGTDFQPTLDSIRYLRECLPGSHLV--RA 271
            ||                |..:.:.|..|:|:|::....:.|..|   ||.:    ||.::  |:
Zfish   471 DNTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFL---RYAQ----GSEVLMSRS 528

  Fly   272 YTTFHIYFGTKHIPKSVPKPHEVFKTGYNCTLPPPYFNVSSGHLYKAQKKLLYPVNVGRNIARDS 336
            ...:||                |:|.|.                       .||||:.||:|...
Zfish   529 NVGYHI----------------VYKEGQ-----------------------FYPVNLLRNVAMGQ 554

  Fly   337 ALTHFILASDIELYPNPGLVKKFLEMIARNEQYLRRKAPRVFPLAIFEVEENSPVPHDKTELQEF 401
            ..|.::..|||:..|..||.:...:.:.:.:....:|| .|.| |...:......|..|.||...
Zfish   555 VNTPYMFLSDIDFLPMYGLYEYLRKSVVQLDMGNTKKA-LVVP-AFETLRYRLSFPKSKAELLSQ 617

  Fly   402 LRTGKAIPFHKRVCASCHGVPKSKEWMSANETDELSVFHIGKRTGYYVHW----EPIYIGTHADP 462
            |..|....|...|....|......:|.:|.             |.|.|.|    ||..:.....|
Zfish   618 LDMGTLFTFRYHVWTKGHAPTDFAKWRTAT-------------TPYRVQWEADFEPYVMVRRESP 669

  Fly   463 HYDER---LSWEGKSDKMPQGYALCVMDYEFHILDNAFLVHKPG------------------IKV 506
            .||.|   ..|    :|:.....|...:|||.:|.||:::|.|.                  :|.
Zfish   670 EYDRRFVGFGW----NKVAHIMELDAQEYEFVVLPNAYMIHMPHAPSFDITKFRSNKQYRACLKT 730

  Fly   507 LKKDNRRAMLSGKTNQLIRKIIYPELKIM 535
            ||::.::.|        .|:..:..||.|
Zfish   731 LKEEFQQNM--------SRRYGFAALKYM 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9171	NP_001162891.1	Glyco_transf_49	212..536	CDD:290607	81/368 (22%)
large1	NP_001004537.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..127
		RfaJ	137..>387	CDD:224359
		GT8_LARGE_C	139..418	CDD:133053	1/2 (50%)
		Xylosyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	139..414
		Glucuronyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	415..757		91/419 (22%)
		Glyco_transf_49	474..743	CDD:290607	73/341 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850