DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9171 and Large2

DIOPT Version :9

Sequence 1:	NP_001162891.1	Gene:	CG9171 / 33807	FlyBaseID:	FBgn0031738	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_006234624.1	Gene:	Large2 / 311202	RGDID:	735214	Length:	715	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	94/419 - (22%)
Similarity:	142/419 - (33%)	Gaps:	106/419 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 GDPSQVIGNIGPGGVAEVNNSQSDGGYIVTGDEKELEERVRSLINCFDHDYHQQTLQRGDFWVLQ 197
            |.|:|.     |.||.::..:      :...||:|         .||:....|.|:.|    |..
  Rat   372 GCPNQF-----PPGVEQLQQA------LAQLDEEE---------PCFEFRQQQLTVHR----VHI 412

  Fly   198 NYVRAEHGDIKCHESITYTTHADYTFLDNLVPLLERWNAPVSIAMHAPGTDFQPTLDSIRYLREC 262
            .::..:....:.|: :|.........|..|..|...|..|:|:|::....:.|
  Rat   413 TFLSHQPPPPRPHD-VTLVAQLSMDRLQMLEALCRHWRGPMSLALYLTDAEAQ------------ 464

  Fly   263 LPGSHLVRAYTTFHIYFGTKHIPKSVPKPHEVFKTGYNCTLPPPYFNVSSGHLYKAQKKLLYPVN 327
                ..:|...|..:....|.:..     |.|::.|       |                |||||
  Rat   465 ----QFLRFVETSPVLSARKDVAY-----HVVYRDG-------P----------------LYPVN 497

  Fly   328 VGRNIARDSALTHFILASDIELYPNPGL---VKKFLEMIARNEQYLRRKAPRVFPLAIFEVEENS 389
            ..||:|...|||.::..|||:..|...|   ::..:|.:|...:  :|||..|.| |...:....
  Rat   498 QLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLALGRR--QRKAALVVP-AFETLHYRF 559

  Fly   390 PVPHDKTELQEFLRTGKAIPFHKRVCASCHGVPKSKEWMSANETDELSVFHIGKRTGYYVHW--- 451
            ..|:.|.||...|..|....|........|.......|..|             :..|.|.|
  Rat   560 SFPNSKAELLTLLDAGSLHTFRYHEWPQGHASTDYTRWREA-------------QAPYRVQWSAD 611

  Fly   452 -EPIYIGTHADPHYDER---LSWEGKSDKMPQGYALCVMDYEFHILDNAFLVHKPGIKVLKKDNR 512
             ||..:.....|.||.|   ..|    :|:.....|...:|||.:|..||.:|.|....|.....
  Rat   612 YEPYVVVPRDCPRYDPRFVGFGW----NKVAHIIELDAQEYEFLVLPEAFSIHLPHAPSLDISRF 672

  Fly   513 RAMLSGKTN----QLIRKIIYPELKIMYG 537
            |   |..|.    |.:::..:.:|...||
  Rat   673 R---SSPTYRDCLQALKEEFHQDLSRRYG 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9171	NP_001162891.1	Glyco_transf_49	212..536	CDD:290607	76/337 (23%)
Large2	XP_006234624.1	GT8_LARGE_C	92..371	CDD:133053
		RfaJ	93..>340	CDD:224359
		Glyco_transf_49	426..660	CDD:290607	68/298 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339829
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750