DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9171 and lge-1

DIOPT Version :9

Sequence 1:	NP_001162891.1	Gene:	CG9171 / 33807	FlyBaseID:	FBgn0031738	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_509833.3	Gene:	lge-1 / 187206	WormBaseID:	WBGene00010716	Length:	631	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	78/383 - (20%)
Similarity:	135/383 - (35%)	Gaps:	89/383 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 DEKELEERVRSLINCFDHDYHQQTLQRGDFWVLQNYVRAEHGDIKCHESITYTTHADYTFLDNLV 228
            |..:|:.|.||.......|...:.|...:|.::.|.:    |.:.....:...|......|::.:
Worm   308 DGSDLKRRRRSFKGNNQKDICHEYLPLDNFRIIPNAI----GRMTKPAELCMVTQFSKDRLNHFL 368

  Fly   229 PLLERWNAPVSIAMHAPGTDFQPTLDSIRYLRECLPGSHLVRAYTTFHIYFGTKHIPKSVPKPHE 293
            .....|..|:|.|::....|.   ||..:.:.|      |.|...|.|:.|         .:|.|
Worm   369 ESANAWRHPISTAVYGKDKDL---LDIAKAVTE------LNRTDITIHLVF---------EEPTE 415

  Fly   294 VFKTGYNCTLPPPYFNVSSGHLYKAQKKLLYPVNVGRNIARDSALTHFILASDIELYPNPGLVKK 358
            .:                       ....|||:|..||:|.:.|...:||.:|::.     :|..
Worm   416 SW-----------------------MLDSLYPINFLRNVAIEHANCKYILMTDVDF-----VVLG 452

  Fly   359 FLEMIARNEQYLRRKAPRVFPLAIFEVEENSPVPHDKTELQEFLR---------TGKAI-PFHKR 413
            ....|......|::|...|.|..      ....|..:..|..||.         ..|.| .|.:.
Worm   453 DYGTIIDQTGNLKQKEVLVIPAL------EMTYPQLRLNLSNFLSRKDLVIEHLLNKTIQTFRET 511

  Fly   414 VCASCHGVPKSKEWMSANETDELSVFHIGKRTGYYVHWEPIYIGTHAD-PHYDER---LSWEGKS 474
            :..|.|......:|:.:|.|         ....|..::||.::....: |.||:|   ..|
Worm   512 IWPSSHVPTNISKWIKSNRT---------YMVNYEKNYEPYFVIKKEECPFYDQRFGGFGW---- 563

  Fly   475 DKMPQGYALCVMDYEFHILDNAFLVHK--PGIKVLKKDNR----RAMLSGKTNQLIRK 526
            :|:.....|.:|:|:|.:...:|::|:  ...|.||:..|    :..|....|:.::|
Worm   564 NKVTHVMQLKMMNYKFLVSPTSFMIHQNHNASKSLKRWRRDPHYQKCLHTLKNKFMKK 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9171	NP_001162891.1	Glyco_transf_49	212..536	CDD:290607	68/335 (20%)
lge-1	NP_509833.3	GT8_LARGE_C	42..317	CDD:133053	3/8 (38%)
		RfaJ	62..>288	CDD:224359
		Glyco_transf_49	354..603	CDD:290607	64/313 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14638
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5095
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.780