DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9171 and XXYLT1

DIOPT Version :9

Sequence 1:	NP_001162891.1	Gene:	CG9171 / 33807	FlyBaseID:	FBgn0031738	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_689744.3	Gene:	XXYLT1 / 152002	HGNCID:	26639	Length:	393	Species:	Homo sapiens

Alignment Length:	198	Identity:	44/198 - (22%)
Similarity:	69/198 - (34%)	Gaps:	62/198 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 EIFESEEKQLVNANADPPAAAAQVADGGAGAPQLANDSGAGAAALGDPSQVIGNIGPGGV----- 147
            |.|.|..|:|..|.|..|||.:        .|.|....|:.|.|.|..::.:...|.|.|
Human    46 ETFSSATKRLKEARAGAPAAPS--------PPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLL 102

  Fly   148 -----AEVNNSQSDGGYIVTGDEKELEERVRSLINCFDHDYHQ------------QTLQRGDFWV 195
                 ||.|.:.          :.:....:|||:.....:.|:            :.:.:|   :
Human   103 MMFTKAEHNAAL----------QAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKG---L 154

  Fly   196 LQNYVRAEHGDIKC----HESITYTTHADYTFLDNLVPLLERWNAPVSIAMHAPGTDFQPTLDSI 256
            |:..:....| .||    |:....|        |.|.|::|......|..:   ||.:.   |||
Human   155 LRELLPPAAG-FKCKVIFHDVAVLT--------DKLFPIVEAMQKHFSAGL---GTYYS---DSI 204

  Fly   257 RYL 259
            .:|
Human   205 FFL 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9171	NP_001162891.1	Glyco_transf_49	212..536	CDD:290607	12/48 (25%)
XXYLT1	NP_689744.3	UDP-alpha-D-xylose binding. /evidence=ECO:0000250\|UniProtKB:Q3U4G3	104..106		0/1 (0%)
		Glyco_tranf_GTA_type	120..383	CDD:299700	22/106 (21%)
		RfaJ	162..>353	CDD:224359	16/61 (26%)
		Interaction with target proteins. /evidence=ECO:0000250\|UniProtKB:Q3U4G3	263..266
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900