DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11029 and plb1

DIOPT Version :9

Sequence 1:	NP_608955.1	Gene:	CG11029 / 33804	FlyBaseID:	FBgn0031735	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_017207306.2	Gene:	plb1 / 560649	ZFINID:	ZDB-GENE-120709-93	Length:	1078	Species:	Danio rerio

Alignment Length:	434	Identity:	139/434 - (32%)
Similarity:	206/434 - (47%)	Gaps:	56/434 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 ENGIQQYTDIDQDLRHLFLNTRQTTLKWALNNI-EALSSRGRREGKLQAPVSKKVPFLCP----- 111
            |:|....:....|..||.........:...||: |.|.::..:| ...|.:|.|    ||
Zfish   584 EDGRPDRSYFSPDCFHLSQKAHTLMARALWNNLMEPLGNKTDKE-DFTAGISLK----CPERSSP 643

  Fly   112 ----------TNNTRSPSP---------------------PTSIEHLRPGDIDIIAAFGDSLSAG 145
                      |.|...|||                     |||:..||||||.::||.||||:||
Zfish   644 YLRTFHNSNYTYNIPEPSPPPPTNWGSDFSCVDTAPSNTLPTSVHSLRPGDIKVVAALGDSLTAG 708

  Fly   146 NGILSNNAIDMINEFRGLTFSGGGLANWRRFVTLPNILKIFNPKLYGFAVSNSLVINHRSSRLNI 210
            .|..:.|.:.:.:|.||:::|.||........|||||.|.|||.::||:...|    .|.:..|:
Zfish   709 FGAKAKNILQLPDEERGVSWSIGGDDTLETVTTLPNIFKKFNPSVFGFSKGKS----KRPNGFNM 769

  Fly   211 AEPMIMSRDLPFQARVLIDLLRRDRHVDMKRHWKLLTVYVGNNDICSDLCHWDTPQSFLDQHARD 275
            |.....::::|.|||.||..|:..:.||.::.|||:|:::|.||:| ..|| |.......::...
Zfish   770 AVGGAKAQNIPAQARDLITALKESKDVDFEKDWKLVTLFIGGNDLC-QYCH-DRAALSSSKYIGH 832

  Fly   276 LRQAFRLLRDHVPRLLINLIVVPNIPLVLSTMTKVPLQCFVVHRVGCHCLINDRLNRTEFNERMD 340
            :|.:..:|.:.|||:|:||:.:..|. .|..:.:..|.|.::.:..|.|.::.|.|..:.|| |.
Zfish   833 IRDSLDMLYNEVPRVLVNLVEILQIE-DLRMIKRDTLGCSLLQKNMCPCFLSPRENSPQMNE-MK 895

  Fly   341 TLTRWQQLDMEIARL----PEFRRQDFAIVAHPMLTKLTAPTLPDGSTDWRFFSHDCFHFSQRGH 401
            .:.|  .|..|..||    ....|.|||:|..|.......|...||..|..|||.||||||:|||
Zfish   896 KVNR--DLQAEAERLVYGGRYDGRHDFAVVLQPFFENTVVPMDKDGKPDVSFFSVDCFHFSERGH 958

  Fly   402 AIISNLLWNSMLLPDDQKPRPSVVPELFERVVCPTAEQPYLVVR 445
            |.::..:||:||.|...|...:.......::.|||.|.|::..|
Zfish   959 AEMAIAIWNNMLEPVGSKQNYNNFTYDRSKIRCPTEEHPFIFTR 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11029	NP_608955.1	Phospholipase_B_like	123..417	CDD:238862	110/297 (37%)
plb1	XP_017207306.2	SGNH_hydrolase	47..260	CDD:321319
		Phospholipase_B_like	326..621	CDD:238862	8/36 (22%)
		Phospholipase_B_like	686..974	CDD:238862	110/297 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583901
Domainoid	1	1.000	157	1.000	Domainoid score	I4114
eggNOG	1	0.900	-	-		E1_KOG3670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1232962at2759
OrthoFinder	1	1.000	-	-		FOG0001722
OrthoInspector	1	1.000	-	-		mtm6595
orthoMCL	1	0.900	-	-		OOG6_104972
Panther	1	1.100	-	-	O	PTHR21325
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.710