Protein Alignment CG11029 and Plb1

DIOPT Version :10

• Sequence 1: NP_608955.1
• Gene: CG11029 / 33804
• FlyBaseID: FBgn0031735
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_620253.1
• Gene: Plb1 / 192259
• RGDID: 621565
• Length: 1450
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 147/489 - (30%)
• Similarity: 232/489 - (47%)
• Gaps: 66/489 - (13%)

  Fly     4 ITYALCLCSLFI-----LFSPLVSANRRVRRQNRSDRLLADIGVRAQSYD--------------- 48
            |..:||.|.|.:     ..:.||..||:.  |..:.:|     :.:..||
  Rat   580 ILRSLCPCVLNLGENSAELAQLVERNRQY--QEETGKL-----IESGRYDTRDDFTVVLQPMFEN 637

  Fly    49 ---PRVPENGIQQYTDIDQDLRHLFLNT--RQTTLKWALNNIEALSSRGRREG-KLQAPV---SK 104
               ||..| |:...:....|..|..:.|  |.....|. |.:|.:..:.|.:. :::.|:   ::
  Rat   638 VVMPRTLE-GLPDSSFFAPDCFHFNVKTHARSAIALWK-NMLEPVGRKTRHQNFEIKVPIMCPNQ 700

  Fly   105 KVPFLCPTNNTR--------------SPSPPTSIEHLRPGDIDIIAAFGDSLSAGNGILS--NNA 153
            ..|||..|.|:.              |.|||||:..|||.||.::||.|||::|||||.|  .:.
  Rat   701 TSPFLSTTKNSNLGHGTSMSCEEKAPSASPPTSVHTLRPADIQVVAALGDSVTAGNGISSQEGDL 765

  Fly   154 IDMINEFRGLTFSGGGLANWRRFVTLPNILKIFNPKLYGFAVSNSLVINHRSSRLNIAEPMIMSR 218
            .|:..::|||::|.||........||||||:.||..|.|::|... .:|..|:.||.|.|...:.
  Rat   766 ADVTTQYRGLSYSAGGDKFLENVTTLPNILREFNGNLTGYSVGTG-DVNSASAFLNQAVPGAKAE 829

  Fly   219 DLPFQARVLIDLLRRDRHVDMKRHWKLLTVYVGNNDICSDLCHWDTPQSFLDQHARDLRQAFRLL 283
            :|..|.:.||..::.|..|:..:.||::||.:|.:|:| |.|. |:.:......:..||.|..:|
  Rat   830 NLASQVQTLIQKMKNDTRVNFHQDWKVITVMIGASDLC-DFCK-DSNRYSAANFSDHLRNALDIL 892

  Fly   284 RDHVPRLLINLIVVPNIPLVLSTMTKVPLQCFVVH-RVGCHCLINDRLNRTEFNERMDTLTRWQQ 347
            ...|||.|:||:...|..::.....|.|.:|.|.. .|.|:|::....:..|. .|::..|:..|
  Rat   893 HKEVPRALVNLVDFMNPSIIRQVFLKNPDKCPVNQTSVLCNCVLTPGEDSHEL-ARLEAFTKSYQ 956

  Fly   348 LDM----EIARLPEFRRQDFAIVAHPMLTKLTAPTLPDGSTDWRFFSHDCFHFSQRGHAIISNLL 408
            ..|    |..|..  .|:||::|..|.|..:..|.|.:|:.|..||:.||...||:.|..::..|
  Rat   957 SSMLQLVESGRYD--TREDFSVVLQPFLFNIRLPILENGNPDTSFFAPDCILLSQKFHTQLARAL 1019

  Fly   409 WNSMLLPDDQKPRPSVVPELFERVVCPTAEQPYL 442
            |.:||.|..:| ..::.|:....:.|||.::|:|
  Rat  1020 WANMLEPLGKK-MDTLDPKELIALACPTKDKPFL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11029	NP_608955.1	Phospholipase_B_like	123..417	CDD:238862	104/300 (35%)
Plb1	NP_620253.1	4 X 308-326 AA approximate repeats. /evidence=ECO:0000255	41..1407		147/489 (30%)
		Phospholipase_B_like	63..321	CDD:238862
		Phospholipase_B_like	387..681	CDD:238862	24/109 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	708..734		7/25 (28%)
		Phospholipase_B_like	733..1028	CDD:238862	104/300 (35%)
		Phospholipase_B_like	1089..1376	CDD:238862
		Necessary for membrane localization. /evidence=ECO:0000269|PubMed:9442065	1408..1450