DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11029 and plb1

DIOPT Version :9

Sequence 1:	NP_608955.1	Gene:	CG11029 / 33804	FlyBaseID:	FBgn0031735	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_031758328.1	Gene:	plb1 / 100495859	XenbaseID:	XB-GENE-997742	Length:	1423	Species:	Xenopus tropicalis

Alignment Length:	447	Identity:	139/447 - (31%)
Similarity:	218/447 - (48%)	Gaps:	79/447 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 PRVPENGIQQYTDIDQDLRHLFL--NTRQTTLKWALNNIEALSSRGRREGKLQAPVSKKVPFLCP 111
            |:.|| |:...:.:..|..|...  :::.....|. |..|.:..:.:.:.     :::.:...||
Frog   590 PKSPE-GVPDRSYMSPDCFHFGEKGHSQSARALWK-NMFEPVGQKTQDQS-----LAEDIGIYCP 647

  Fly   112 TNN---------------TRSPSP-----------------PTSIEHLRPGDIDIIAAFGDSLSA 144
            |.:               |.:|.|                 |||:..|||.|:.::||.||||:|
Frog   648 TQSDPFVKTARNSNFAYPTTAPDPIHGSKVTCADKSPSVSKPTSVHALRPADVAVVAAIGDSLTA 712

  Fly   145 GNGILS--NNAIDMINEFRGLTFSGGGLANWRRFVTLPNILKIFNPKLYGFAVSNSLVINHRSSR 207
            ||||.|  |:.:|::|.:|||::|.||.:...|..||||||..|||.|.||:........| :|.
Frog   713 GNGIASKPNDVLDVLNMYRGLSWSIGGDSTLDRVTTLPNILLEFNPLLTGFSTGTGNKTLH-NSY 776

  Fly   208 LNIAEPMIMSRDLPFQARVLIDLLRRDRHVDMKRHWKLLTVYVGNNDICSDL--CHWDTPQSFLD 270
            ||.|.|...:.:||.|.:.||..::.||..:....||::|:.:|.||:||..  .::.:.::|:|
Frog   777 LNEAVPGAKAFNLPEQVKDLIAQMKEDRRFNYNNDWKVITILIGPNDLCSSCSDANFYSTKNFID 841

  Fly   271 QHARDLRQAFRLLRDHVPRLLINLIVVPNI-PL---VLSTMTKVPLQCFVVHRVGCHCLINDRLN 331
            .    :::|..||...|||..:||:.|.:| ||   ||....|.|:   ::.::.|.||:|...|
Frog   842 Y----IQEALDLLHKEVPRAFVNLVEVMDIYPLREAVLDPRVKCPV---LITKMLCPCLLNIADN 899

  Fly   332 R------TEFNERMDTLTRWQQLDMEIARLPEFRRQDFAIVAHPMLTKLTAPTLPDGSTDWRFFS 390
            .      .|||......|  ||| ::..|..  .:.||.:|..|.......|:||:|:.|..|.:
Frog   900 SQELKIVREFNSGYQRNT--QQL-IDTGRYD--TKDDFTVVLQPFFRNPKIPSLPNGTPDASFMA 959

  Fly   391 HDCFHFSQRGHAIISNLLWNSMLLPDDQKPRPSVVPELF-----ERVVCPTAEQPYL 442
            .||||.||:.|:.::.:||.:||.|...|      .:|.     |.:.|||.:||:|
Frog   960 PDCFHLSQKSHSQMARMLWKNMLEPVGMK------TDLLDFAAAETLTCPTPDQPFL 1010

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11029	NP_608955.1	Phospholipase_B_like	123..417	CDD:238862	113/307 (37%)
plb1	XP_031758328.1	SGNH_hydrolase	58..258	CDD:412717
		Phospholipase_B_like	335..630	CDD:238862	9/41 (22%)
		Phospholipase_B_like	691..986	CDD:238862	113/307 (37%)
		Phospholipase_B_like	1051..1337	CDD:238862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4094
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1232962at2759
OrthoFinder	1	1.000	-	-		FOG0001722
OrthoInspector	1	1.000	-	-		otm47574
Panther	1	1.100	-	-	O	PTHR21325
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.110