DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and Abca2

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	XP_006233707.2	Gene:	Abca2 / 79248	RGDID:	620238	Length:	2435	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	83/275 - (30%)
Similarity:	143/275 - (52%)	Gaps:	26/275 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEVRNGYKYYGSKSNPKIV-LNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVL 67
            |::.|..|.|.|:...:|: :::|.:.|..|..:||||.:|.|||:....:.|.....|||..|.
  Rat  2052 VKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVN 2116

  Fly    68 GAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGL--TDER--IR---EKFKLLKE 125
            |....:....|..| :|:.||..||.:|:|.:|.:..:.|:.|:  .||.  :|   ||.:|.|
  Rat  2117 GHSVLKDLLQVQQS-LGYCPQFDALFDELTAREHLQLYTRLRGIPWKDEAQVVRWALEKLELTK- 2179

  Fly   126 LLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKL 190
                 .|.:.....|||.:|:||.|.|:|..|..:.|||||.|:||..|..:|:.:::..:..:
  Rat  2180 -----CADKPAGSYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGR- 2238

  Fly   191 AVIITTHYIEEAKQANC--IGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQ 253
            :|::|:|.:||. :|.|  :.:|.||.|....:..::..:||     |.::|..:.:.:::....
  Rat  2239 SVVLTSHSMEEC-EAVCTRLAIMVNGRLRCLGSIQHLKNRFG-----DGYMITVRTKSSQNVKDV 2297

  Fly   254 IMDHNKNQALPAAVL 268
            :...|:|  .|.|:|
  Rat  2298 VRFFNRN--FPEAML 2310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	83/275 (30%)
		P-loop_NTPase	4..222	CDD:304359	74/227 (33%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
Abca2	XP_006233707.2	rim_protein	1..2369	CDD:130324	83/275 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810