DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and abca3b

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	XP_009297489.1	Gene:	abca3b / 564344	ZFINID:	ZDB-GENE-050517-2	Length:	1703	Species:	Danio rerio

Alignment Length:	278	Identity:	83/278 - (29%)
Similarity:	144/278 - (51%)	Gaps:	40/278 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLG------AK 70
            |.|.:|  .:.:::|::.|.:|..:||||.:|.||||....:.|...:..|:..:.|      .|
Zfish  1387 YSGGQS--LLAVDRLSLAVGKGECFGLLGFNGAGKTTTFKMLTGDESITSGDAFIDGYSILTDVK 1449

  Fly    71 PGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKF------KLLKELLQL 129
            ..:       .|:|:.||..|:::.||.:||:..:.|:.|     |.||:      .:|:.||..
Zfish  1450 KVQ-------QRIGYCPQFDAVLDHMTGRETLSMYARLRG-----IPEKYVTACVENVLRSLLLE 1502

  Fly   130 PPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVII 194
            |.|.::::..|||.:|:||...|:|..|.::.||||:.|:||:.|..:|| .:..||.|..|:||
Zfish  1503 PHADKLVRSYSGGNKRKLSAGMALIGGPPVIFLDEPSTGMDPVARRLLWD-AITRTRESGKAIII 1566

  Fly   195 TTHYIEEAKQANC--IGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILS----QRQGNEDELAQ 253
            |:|.:||. :|.|  :.:|.||......:|.::..|||:     .:.:|:    :.:..|.:|..
Zfish  1567 TSHSMEEC-EALCTRLAVMVNGQFKCLGSPQHLKSKFGS-----GYTLLAKVRVETELEESDLQL 1625

  Fly   254 IMDHNKNQALPAAVLPPE 271
            ..|..:: ..|.::|..|
Zfish  1626 FKDFIES-TFPGSLLKDE 1642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	83/278 (30%)
		P-loop_NTPase	4..222	CDD:304359	72/223 (32%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
abca3b	XP_009297489.1	AAA	1..>95	CDD:333001
abca3b	XP_009297489.1	AAA	<122..1695	CDD:333001	83/278 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910