DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and abca8

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	XP_031749971.1	Gene:	abca8 / 549630	XenbaseID:	XB-GENE-1005441	Length:	1619	Species:	Xenopus tropicalis

Alignment Length:	267	Identity:	78/267 - (29%)
Similarity:	136/267 - (50%)	Gaps:	17/267 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGA 69
            :|:.|..::  |.|.|.....::..|.:|.:.||||.:|.||||.:..:.|:.|...|||::.|.
Frog  1280 KVKKGKSFF--KKNKKAATKNISFCVRKGEVLGLLGPNGAGKTTSIYMLAGEIRPTAGEVLLCGT 1342

  Fly    70 KPGEPGSGV--PGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPP- 131
            .|.:..:..  |...:|:.||:..|...:|||:.:..:..:.||..:......|.:.|.|:|..
Frog  1343 DPDKSQNSQYDPTGSLGYCPQDNPLWPNLTVKQHLEIYAAVKGLKKKDAETAIKRVSEALELKEH 1407

  Fly   132 ARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITT 196
            ..:..::.|.|..|::.||.:|:.:|.:::||||:.||||..::::|..:....||.....|:||
Frog  1408 LEKAARKLSAGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQQRLWRAIRSAFRNKDRGAILTT 1472

  Fly   197 HYIEEAKQANC--IGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNE-----DELAQI 254
            ||:||| :|.|  :.:|.:|.|....:...:..|||    :...|.:..:..|:     :|:.||
Frog  1473 HYMEEA-EAVCDRVAIMVSGKLRCIGSIQQLKSKFG----KGYLLEIKVKNSNQVDQIHNEIIQI 1532

  Fly   255 MDHNKNQ 261
            ..|...|
Frog  1533 FPHAARQ 1539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	78/267 (29%)
		P-loop_NTPase	4..222	CDD:304359	68/221 (31%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	78/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7652
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000