DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and Abcg2

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_852046.1	Gene:	Abcg2 / 312382	RGDID:	631345	Length:	657	Species:	Rattus norvegicus

Alignment Length:	424	Identity:	92/424 - (21%)
Similarity:	168/424 - (39%)	Gaps:	91/424 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNG--GEVVV 66
            |:|::|:..  .|:..|.:|:.:| .:|:..:..:||.:|.||::||..:..::...|  |:|::
  Rat    46 VKVKSGFLV--RKTAEKEILSDIN-GIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLSGDVLI 107

  Fly    67 LGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGL-----TDERIREKFKLLKEL 126
            .||.  :|.:....|  |::.|:..::..:||:|.: .|.....|     |.|:......::|||
  Rat   108 NGAP--QPANFKCSS--GYVVQDDVVMGTLTVRENL-QFSAALRLPKAMKTHEKNERINTIIKEL 167

  Fly   127 -----LQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTR 186
                 .......|..:..|||:::|.|....:|.||.:|.|||||.|||......:...|...::
  Rat   168 GLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSK 232

  Fly   187 NSKLAVIITTHYIEEA--KQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIE--------DAFLIL 241
            ..: .:|.:.|....:  |..:.:.|:.:|.|:........:..|.:....        |.||.:
  Rat   233 QGR-TIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPADFFLDV 296

  Fly   242 SQRQGNEDELAQIMDHNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEEPLNENRKKIFF--TTK 304
            .    |.|..|.:::..:..              ||.|..| :|...|:|:.||..:.:.  |..
  Rat   297 I----NGDSSAVMLNRGEQD--------------HEANKTE-EPSKREKPIIENLAEFYINSTIY 342

  Fly   305 GRVKA--------------------------------LMTKNFVQLFRQPSGIIFMLLFPIIQ-- 335
            |..||                                :..::|..|...|...:..|:..:|.
  Rat   343 GETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGL 407

  Fly   336 -LTCFYLAIGKTPTNLE--IGVYSGEVENYGECF 366
             :...|..:...||.::  .||:.....|  :||
  Rat   408 IIGALYFGLKNDPTGMQNRAGVFFFLTTN--QCF 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	69/299 (23%)
		P-loop_NTPase	4..222	CDD:304359	59/231 (26%)
		ABC2_membrane_3	322..702	CDD:289468	11/50 (22%)
		ABC2_membrane	469..664	CDD:279410
Abcg2	NP_852046.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
Abcg2	NP_852046.1	3a01204	46..651	CDD:273361	92/424 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000