DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11147 and Abca7

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_997481.1	Gene:	Abca7 / 299609	RGDID:	1303134	Length:	2170	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	85/329 - (25%)
Similarity:	151/329 - (45%)	Gaps:	59/329 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLG 68
            |.:|...|::  :.:|:..|..||::...|.|...||.:|.||||.||.:.|....:.|...:||
  Rat   805 VSIRGLKKHF--RGSPQPALRGLNLDFYEGHITAFLGHNGAGKTTTLSILSGLFPPSSGSASILG 867

  Fly    69 ---------AKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERI-REKFKLL 123
                     .:|          .:|..||...|.:.:||:|.::::||:.|::...| .|:..|:
  Rat   868 HDVQTNMAAIRP----------HLGICPQYNVLFDMLTVEEHVWFYGRLKGVSAAAIDSEQEHLI 922

  Fly   124 KELLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNS 188
            :::..:|......:..|||.||:||.|.|.:....::|:||||.|:||..|..||:.|::.....
  Rat   923 RDVGLIPKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVIMDEPTAGVDPASRRGIWELLLKYREGR 987

  Fly   189 KLAVIITTHYIEEAK-QANCIGLMRNGVLLAEDTPTNIMIKFG----------TQSI-------- 234
            .|  |::||:::||: ..:.:.::.:|.|....:|..:....|          :||:
  Rat   988 TL--ILSTHHLDEAELLGDRVAMVASGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDLKGD 1050

  Fly   235 -EDAFLILSQRQGNEDELAQIM-----DHNKNQ--------ALPAAVLPPEVIDTHEPNMPEKQP 285
             ||.  ...::.|:|.:.|..:     .|..:|        ..|:|.|..|::..|.|.....:.
  Rat  1051 TEDP--RREKKSGSEGKTADTVLTRDGPHRSSQVPAPDAVPVTPSAALILELVQRHVPGAQLVEE 1113

  Fly   286 IPFE 289
            :|.|
  Rat  1114 LPHE 1117

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	83/320 (26%)
		P-loop_NTPase	4..222	CDD:304359	66/228 (29%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
Abca7	NP_997481.1	rim_protein	1..2127	CDD:130324	85/329 (26%)
		ABC2_membrane	<557..742	CDD:304374
		ABC_subfamily_A	805..1024	CDD:213230	67/232 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1044..1086		7/43 (16%)
		ABC_subfamily_A	1818..2038	CDD:213230
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2129..2170
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900