DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and Abca3

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_001034670.1	Gene:	Abca3 / 27410	MGIID:	1351617	Length:	1704	Species:	Mus musculus

Alignment Length:	274	Identity:	82/274 - (29%)
Similarity:	142/274 - (51%)	Gaps:	11/274 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGAKPGEPG 75
            |.|..:: |.:.::::::.|.:|..:||||.:|.||||....:.|:..:..|:..| |.......
Mouse  1388 KVYDQRA-PLLAVDRISLAVQKGECFGLLGFNGAGKTTTFKMLTGEETITSGDAFV-GGYSISSD 1450

  Fly    76 SGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFK-LLKELLQLPPARQMIKQC 139
            .|....|:|:.||..||::.||.:|.:..:.|:.|:.:..|....: .|:.||..|.|.:::|..
Mouse  1451 IGKVRQRMGYCPQFDALLDHMTGREMLVMYARLRGIPERLINACVENTLRGLLLEPHANKLVKTY 1515

  Fly   140 SGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYIEEAKQ 204
            |||.:|:||...|:|.:|.::.||||:.|:||:.|..:|| .|...|.|..|::||:|.:||. :
Mouse  1516 SGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRLLWD-TVARARESGKAIVITSHSMEEC-E 1578

  Fly   205 ANC--IGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQIMDHNKNQALPAAV 267
            |.|  :.:|..|......:|.::..|||:.....|.:....:|...:|....:|    ...|.::
Mouse  1579 ALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYSLQAKVRSEGKQDALEEFKAFVD----LTFPGSI 1639

  Fly   268 LPPEVIDTHEPNMP 281
            |..|..|....::|
Mouse  1640 LEDEHQDMVHYHLP 1653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	82/274 (30%)
		P-loop_NTPase	4..222	CDD:304359	69/213 (32%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
Abca3	NP_001034670.1	rim_protein	1..>43	CDD:130324
Abca3	NP_001034670.1	rim_protein	<206..1699	CDD:130324	82/274 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810