Protein Alignment CG11147 and abt-5

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_001364572.1
• Gene: abt-5 / 173081
• WormBaseID: WBGene00000023
• Length: 1582
• Species: Caenorhabditis elegans
• Alignment Length: 895
• Identity: 179/895 - (20%)
• Similarity: 315/895 - (35%)
• Gaps: 292/895 - (32%)

  Fly     1 MAAVEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVV 65
            :|.:|:....|.|   .|.:..:|.|::..:||.:..|||.:||||:|....|.|..:...|:|:
 Worm   448 IADIELSGLVKVY---QNGEKAVNGLSLRAIRGQVSILLGHNGCGKSTTFGMITGMHQATEGKVM 509

  Fly    66 VLGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFK-----LLKE 125
            : |..............:|:.||...:.:|:||.|.:.....:.|.:.   ...||     |||:
 Worm   510 I-GGIDANANRAEARELIGYCPQYNPIYDELTVWEHLRLVNALKGRSG---GSDFKMDAESLLKQ 570

  Fly   126 LLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDF--LVETTRNS 188
            :........:.|..|||.:|:|....|||....:::|||||.|:||..|..:.:.  ||:..|
 Worm   571 IELTDKRNTLAKNLSGGMKRKLCVCMAMIGGSRVILLDEPTAGMDPSARIDVQNMLALVKADR-- 633

  Fly   189 KLAVIITTHYIEEA-KQANCIGLMRNGVLLAEDTPTNIMIKFG------------------TQSI 234
              .:::||||::|| |..:.|.:|.:|.:.|..:...:..|:|                  .:|.
 Worm   634 --TILLTTHYMDEAEKLGDWIFVMSHGKMAASGSKHYLKQKYGGGMLLTLVFKSVHDPMRPRKSY 696

  Fly   235 EDAF---------LILSQRQGNEDELAQIMDHNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEE 290
            |.|:         .::...:|...|:: |::..|:: ||..:...|.:...:.|.||.|.:  |.
 Worm   697 ETAYDVCKTVCSTALVKDERGQMIEIS-ILETEKSR-LPTLLKILESVMEEDYNNPEFQAL--EP 757

  Fly   291 PLNENRKKIFFTTKG-------------------------------------------------- 305
            .:.|..:.:...|.|
 Worm   758 DIQEKCRTLELATIGVSMSSLEQVFIKIGDECDDIMNGTGVDKKTERQEKFSTLVQYKIQQPKQG 822

  Fly   306 ------RVKALMTKNFVQLFRQPSGIIFMLLFPIIQLTCF---YLAIGKTPTNLEIGVYSGEVEN 361
                  .|.||:.|....|:|.|..|...::.|::.|..|   :|.:...|..|      .::|:
 Worm   823 FSKLMMVVWALLQKRAYYLYRNPVQITLQIILPLLTLWLFAVPFLRLEPKPPKL------SDIES 881

  Fly   362 YGEC-FDENLVTVYKDSDNESCLFNKLSC----RYIRVLGDD---VATRKYYASEADALNDAKRA 418
            :... :..:.|.:..:::|:..|.|.|:.    ..::|..:|   ...:||          ::..
 Worm   882 FDPSQYPHSTVLLQLENENDDRLANYLNSFSNFEVVKVGYNDHYGYLVKKY----------SQVF 936

  Fly   419 TTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQQVAYFMQ-----RKLRDKFS 478
            .|:|::.......||....:..|                    |:..|..|.     ..|||.
 Worm   937 KTLGFIVKVNKKGDSKFYKISQG--------------------DKNAAILMNIIASAMYLRDP-- 979

  Fly   479 TFMRSVVKDCNVSTAIV---DLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVF-- 538
                ||.|..:|::.::   |..::::.             .|...:...:|||  |:.|.:|
 Worm   980 ----SVTKLPHVTSRVIWMNDPKIKYEG-------------LASFFLFENIFFL--LVLAGIFIQ 1025

  Fly   539 -----ISERMDGIWDRTLLAGVS-----ATEMLWAHLLTQLIIMALQSFEVIMYIGLVFDTYNNG 593
                 |.|::.....:..|.|:|     ....||..||.        :|.::..||.:..
 Worm  1026 STVYLIEEKICKFAHQQYLTGLSTIAYWGVVFLWDFLLF--------TFFLLYTIGFLIS----- 1077

  Fly   594 DTTTLIGLL------TLTAFCGMLFGL-----FISVFCKSHTEANFVATGAFYPMIILCGLLWPL 647
                 .|:|      .:..|.|:||..     ..|....:.|..||:       :.:.|.:.|..
 Worm  1078 -----FGVLQGHIHEIVVIFYGLLFYFAPLVYLTSALINTPTRGNFL-------LYMFCCIPWLA 1130

  Fly   648 ESMPQFLQDLVMVLPFTIPSISARNVIEKGWSITHEKVYNGFLVMAG------------------ 694
            .|:...|.:...:..::       :.||.|:.|.:..:  |||  ||
 Worm  1131 YSIVSELHNFPPIQKYS-------DEIEYGFRIFNPSI--GFL--AGLMKIAALNYPKSGLDKHF 1184

  Fly   695 ------WTI--IFFVL-------------------------CLIGIRRKA 711
                  ||.  |||.|                         |..|.||::
 Worm  1185 EHLTNLWTYEGIFFELMFLFFGGIFLTILLGCATLKPFRRACFRGTRRRS 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	71/275 (26%)
		ABC2_membrane_3	322..702	CDD:463674	81/447 (18%)
		YadH	513..710	CDD:440604	51/270 (19%)
abt-5	NP_001364572.1	ABC2_membrane_3	<158..391	CDD:463674
		rim_protein	<419..1569	CDD:130324	179/895 (20%)