DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11147 and abt-2

DIOPT Version :9

Sequence 1:	NP_608954.1	Gene:	CG11147 / 33803	FlyBaseID:	FBgn0031734	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	NP_490949.3	Gene:	abt-2 / 171782	WormBaseID:	WBGene00000020	Length:	2146	Species:	Caenorhabditis elegans

Alignment Length:	286	Identity:	80/286 - (27%)
Similarity:	140/286 - (48%)	Gaps:	38/286 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AVEVRNGYKYYGSKSNPKIV-LNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVV 66
            |:.|||..|.|    ||::: :..::..|..|..:||||.:|.||||..:.:..:.|...|.:.:
Worm  1801 ALIVRNLAKAY----NPELLAVKGISFAVEPGECFGLLGLNGAGKTTTFAMLTAKIRPGHGSIEM 1861

  Fly    67 LGAKPGEPGSGVPGS--------RVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLL 123
            ...:..      .||        ::|:.||..||..:::.:|.:.::.||.|:...:|......|
Worm  1862 QNTRIN------TGSFSDVRNFQQLGYCPQFDALNMKLSTRENLKFYARIRGIVPTQIDSIIDRL 1920

  Fly   124 KELLQLPP-ARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRN 187
            ...|.|.| |.......|||.:|:||.|.|::..|.|:.||||:.|:||..::.:|..:....::
Worm  1921 LIALHLRPYANTQTSSLSGGNRRKLSVAVALVSQPSLIFLDEPSAGMDPGSQQFLWKVIERLCKS 1985

  Fly   188 SKLAVIITTHYIEEAKQANC--IGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQG---N 247
            .| ||::|:|.:||. :|.|  |.:|..|.:.......::..|:|..|      :|:.:.|   |
Worm  1986 GK-AVVLTSHSMEEC-EALCTRIAIMDRGRIRCLGGKQHLKSKYGKGS------MLTMKMGKDEN 2042

  Fly   248 EDELAQIM-----DHNKNQALPAAVL 268
            ..|:|.||     |.::.:|:..:.:
Worm  2043 AKEIAGIMRSKLGDGSRVEAIHCSTI 2068

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	1..282	CDD:224054	80/286 (28%)
		P-loop_NTPase	4..222	CDD:304359	67/229 (29%)
		ABC2_membrane_3	322..702	CDD:289468
		ABC2_membrane	469..664	CDD:279410
abt-2	NP_490949.3	rim_protein	39..2117	CDD:130324	80/286 (28%)
		ABC_subfamily_A	929..1134	CDD:213230
		ABC_subfamily_A	1802..2024	CDD:213230	67/233 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810