Protein Alignment CG11147 and Mdr49

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_061504490.1
• Gene: Mdr49 / 1276325
• VectorBaseID: AGAMI1_004587
• Length: 1304
• Species: Anopheles gambiae
• Alignment Length: 617
• Identity: 126/617 - (20%)
• Similarity: 230/617 - (37%)
• Gaps: 130/617 - (21%)

  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLN--GGEVVV 66
            ::..|.:..|.::::.: ||..||:.:..|....|:|.|||||:|.|..|  ||..:  .|.|.:
Mosquito   429 IKFSNVFFRYPARNDVQ-VLQGLNLEIKTGQTVALVGPSGCGKSTCLQLI--QRLYDPLSGSVTI 490

  Fly    67 LGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTD------ERIREKFKLLKE 125
            .|.|..|...|...|.:|.:.||..|. ..|:.|.|     .||..|      ||..:.......
Mosquito   491 DGTKVSELNIGWLRSFIGLVGQEPVLF-ATTIAENI-----RYGNPDASQSEIERAAKIANCHSF 549

  Fly   126 LLQLPPA-RQMI----KQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETT 185
            :.:||.. ..||    .|.||||::|::.|.|::.:|::|:|||.|..|||...:::.|.|...:
Mosquito   550 ITKLPNGYGTMIGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDPNSEKRVQDALERAS 614

  Fly   186 RNSKLAVIITTHYIEEAKQANCIGLMRNGVLLAEDTPTNIM----------IKFGTQ-------S 233
            :..  ..::.:|.:.....|:.|..:..|:::.:.|...:|          :..|:|       |
Mosquito   615 KGR--TTLVVSHRLSTITNADKIVYIDKGLVMEQGTHEELMAARGLYYDLVVASGSQKTVDDDES 677

  Fly   234 IEDAFLILSQRQGNEDELAQIMD--------HNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEE 290
            :..|...||.||.:.|:.|:..|        ..||:.....|....::...:.|.||...|.|
Mosquito   678 VPMAPSALSMRQESVDDGAEASDDESDSGKSDEKNEEEQEEVYHVSLMRLLKLNAPEWHYILF-- 740

  Fly   291 PLNENRKKIFFTTKGRVKALMT----KNFVQLFRQPSGII--------------FMLLFPII--- 334
                          |...|::.    ..|..||.:..||:              :..||.::
Mosquito   741 --------------GCAAAIVVGASFPAFAVLFGEMYGILSVADPEYVKEESNFYSFLFLVLGLI 791

  Fly   335 -------QLTCFYLAIGKTPTNLEIGVYSGEVENYGECFDENLVTVYKDSDNESCLFNKLSCRYI 392
                   |...|.:|..:..:.|....:...|......|||:.              |.:.....
Mosquito   792 TGVGTFFQTYLFNIAGVRLTSRLRQKSFKAIVSQDMAWFDESR--------------NAVGALCA 842

  Fly   393 RVLGDDVATRKYYASEADALNDAKRATTVGY-LHFAQNFSDSILSVMEDGIHSSDGAVDHAELSI 456
            |:.||..:.:....:...:|..|.....:|. :.|..:::.:::|::         |:.....||
Mosquito   843 RLSGDCASVQGATGTRIGSLLQAASTICIGVGISFFYSWNLTLVSIV---------AIPVTLASI 898

  Fly   457 HIDMTDQQVAYFMQRKLRDKFSTFMRSVVKDCNVSTAIVDLPVQFQEPIFGSTDIEFQQYC---- 517
            .::....|.:...:::.::..:......:.:.....::.......|.  :|...::....|
Mosquito   899 TLESRYSQTSSLKEKQSQEGATKLAVEAISNIRTVASLGQEKHVLQR--YGEETVKIDDACRRKT 961

  Fly   518 -------APGVVMTMVFFLATLMTAAVFISER 542
                   |.|.||....:...|......:||:
Mosquito   962 RLRGTVFALGQVMPFAGYGLALFYGGKLVSEK 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	73/270 (27%)
		ABC2_membrane_3	322..702	CDD:463674	35/257 (14%)
		YadH	513..710	CDD:440604	8/41 (20%)
Mdr49	XP_061504490.1	None