Protein Alignment CG11147 and abca2

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_031746716.1
• Gene: abca2 / 100498548
• XenbaseID: XB-GENE-969968
• Length: 2496
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 138/596 - (23%)
• Similarity: 226/596 - (37%)
• Gaps: 171/596 - (28%)

  Fly    11 KYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGAKPGEPG 75
            |.|  |:..|:.||:|::|:....:...||.:|.||||.:|.:.|......|...:.|.......
 Frog  1047 KIY--KTGKKLALNKLSLNLHENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEM 1109

  Fly    76 SGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPPAR-QMIKQC 139
            :.:..| :|..||...|.:::||:|.::::.|:.|:.:|.||::...:.|.|:|...| .:::..
 Frog  1110 NEIRKS-MGMCPQHNVLFDKLTVEEHLWFYSRLKGMAEEEIRKEMDKMIEDLELSNKRHSLVQTL 1173

  Fly   140 SGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYIEEAK- 203
            |||.:|:||.|.|.:...:.:||||||.|:||..|..|||.:::..:..  .::::||:::||.
 Frog  1174 SGGMKRKLSVAIAFVGGSKAVILDEPTAGVDPYARRAIWDLILKYKQGR--TILLSTHHMDEADL 1236

  Fly   204 QANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQIMDHNKNQALP-AAV 267
            ..:.|.::.:|.|....:|                |.|....|:..:|..:    |||:.| ...
 Frog  1237 LGDRIAIISHGKLKCYGSP----------------LFLKSTYGDGYKLTVV----KNQSGPDTGH 1281

  Fly   268 LPPEVIDTHEPNMPEKQPIPFEEPLNENRKKIFFTTKGRVKALMTKNFVQLFRQPSGIIFMLLFP 332
            ..|..|.            |..||              ||...: |.:|
 Frog  1282 TGPSCIS------------PCSEP--------------RVSQFI-KKYV---------------- 1303

  Fly   333 IIQLTCFYLAIGKTPTNLEI-----GVYSGEVENYGECFDENLVTVYKDSDNESCLFNKLSCR-- 390
               .:|  |.:..|.|.|..     .|..|..|...:..::||      ||.|...|..:...
 Frog  1304 ---ASC--LLVSDTNTELSYILPSESVRKGCFERLFQHLEQNL------SDLELTSFGLMDTTLE 1357

  Fly   391 --YIRVLGDDVATRKYYASEAD---------------------ALNDAKRATTVGYLHFAQNFSD 432
              :::|..:|.:...   |:||                     .|.||.....|...:||.....
 Frog  1358 EVFLKVSEEDQSLEN---SDADIKESKKDTLRPLIQPDGGTGSPLTDALEKPEVELNNFASEAKT 1419

  Fly   433 S-ILSVMEDGIHSSDGAV-----------------------DHAELSIHIDMTDQQV-----AYF 468
            | ..|.:..|..||.|:|                       |...||:|...|::||     :|.
 Frog  1420 SQSPSSLRSGSSSSVGSVRGDEGGAYAEFYGDYSPLFDNLQDAENLSLHEPETEEQVLDGQGSYK 1484

  Fly   469 MQ---RKLRDKFSTFMRSVVKDCNVSTAIVDLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLA 530
            ::   .|||.    |...:||..:.:..              :|...|.|...|      .||:.
 Frog  1485 LEGSWLKLRQ----FHGLIVKRFHCAKR--------------NTKALFSQILLP------AFFVC 1525

  Fly   531 TLMTAAVFISE 541
            ..||.|:.:.|
 Frog  1526 VAMTVALSVPE 1536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	67/235 (29%)
		ABC2_membrane_3	322..702	CDD:463674	56/282 (20%)
		YadH	513..710	CDD:440604	9/29 (31%)
abca2	XP_031746716.1	rim_protein	1..2430	CDD:130324	138/596 (23%)