DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14006 and NEMP1

DIOPT Version :9

Sequence 1:	NP_001260104.1	Gene:	CG14006 / 33802	FlyBaseID:	FBgn0031733	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_011536358.1	Gene:	NEMP1 / 23306	HGNCID:	29001	Length:	492	Species:	Homo sapiens

Alignment Length:	336	Identity:	64/336 - (19%)
Similarity:	116/336 - (34%)	Gaps:	104/336 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 GIYTSKPFVLTLEVIS------------FDLERVSQFTFGIVLWLSCPLLADSLLFFYCSAAALG 190
            |:|::|. .|.:|:|.            ||.:....|..|::|:....||:.|.:|:|.:...:|
Human   180 GLYSTKT-CLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVG 243

  Fly   191 AHLAGLLAVAATLMASDGERYLRLGTLKVNFKLVLNERPTVITLALVSGAW-----LLKSASQRC 250
            . :|.||.:...|.                 |.:..:.|..:.|.   |.|     |::...:..
Human   244 I-VASLLIIIFILS-----------------KFMPKKSPIYVILV---GGWSFSLYLIQLVFKNL 287

  Fly   251 SFLWRCTLFRRLHHRLLKGTSYLLIL----TASDHRGFGM---------TCLM---LLMPWPELL 299
            ..:|||.....|.:.|..|.....:.    ...:.|...:         .|.|   :.:|...|.
Human   288 QEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALA 352

  Fly   300 TV------------IRWLKTLYACYK--RGSVKPM-----------VQVEIENQ----------D 329
            .:            |:||  ...|.|  :|:.||:           :|.|:|.:          :
Human   353 IIIIALCTKNLEHPIQWL--YITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCN 415

  Fly   330 VPYQDSYLRIVRSEYDNR-------SSESSGFSRSFSQNKHNMGFYREQEDQDNALIYESRRPTE 387
            .|...::..:.|.:...|       ||..:....|..:.::.:|....|::     |||.....|
Human   416 SPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDE-----IYEEASSEE 475

  Fly   388 RNCFNRCHQCT 398
            .:.::||...|
Human   476 EDSYSRCPAIT 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14006	NP_001260104.1	DUF2215	146..345	CDD:287228	48/266 (18%)
NEMP1	XP_011536358.1	DUF2215	202..446	CDD:287228	48/266 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005187
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13598
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.100