Protein Alignment CG14006 and NEMP1

DIOPT Version :10

• Sequence 1: NP_608953.1
• Gene: CG14006 / 33802
• FlyBaseID: FBgn0031733
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: XP_011536358.1
• Gene: NEMP1 / 23306
• HGNCID: 29001
• Length: 492
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 64/336 - (19%)
• Similarity: 116/336 - (34%)
• Gaps: 104/336 - (30%)

  Fly   138 GIYTSKPFVLTLEVIS------------FDLERVSQFTFGIVLWLSCPLLADSLLFFYCSAAALG 190
            |:|::|. .|.:|:|.            ||.:....|..|::|:....||:.|.:|:|.:...:|
Human   180 GLYSTKT-CLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVG 243

  Fly   191 AHLAGLLAVAATLMASDGERYLRLGTLKVNFKLVLNERPTVITLALVSGAW-----LLKSASQRC 250
            . :|.||.:...|.                 |.:..:.|..:.|.   |.|     |::...:..
Human   244 I-VASLLIIIFILS-----------------KFMPKKSPIYVILV---GGWSFSLYLIQLVFKNL 287

  Fly   251 SFLWRCTLFRRLHHRLLKGTSYLLIL----TASDHRGFGM---------TCLM---LLMPWPELL 299
            ..:|||.....|.:.|..|.....:.    ...:.|...:         .|.|   :.:|...|.
Human   288 QEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALA 352

  Fly   300 TV------------IRWLKTLYACYK--RGSVKPM-----------VQVEIENQ----------D 329
            .:            |:||  ...|.|  :|:.||:           :|.|:|.:          :
Human   353 IIIIALCTKNLEHPIQWL--YITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCN 415

  Fly   330 VPYQDSYLRIVRSEYDNR-------SSESSGFSRSFSQNKHNMGFYREQEDQDNALIYESRRPTE 387
            .|...::..:.|.:...|       ||..:....|..:.::.:|....|::     |||.....|
Human   416 SPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDE-----IYEEASSEE 475

  Fly   388 RNCFNRCHQCT 398
            .:.::||...|
Human   476 EDSYSRCPAIT 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14006	NP_608953.1	NEMP	147..>185	CDD:463008	13/49 (27%)
NEMP1	XP_011536358.1	NEMP	202..446	CDD:463008	48/266 (18%)