DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11149 and GXYLT2

DIOPT Version :9

Sequence 1:	NP_608952.2	Gene:	CG11149 / 33800	FlyBaseID:	FBgn0031732	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001073862.1	Gene:	GXYLT2 / 727936	HGNCID:	33383	Length:	443	Species:	Homo sapiens

Alignment Length:	273	Identity:	53/273 - (19%)
Similarity:	87/273 - (31%)	Gaps:	115/273 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 VSFHVYFPNQHMPEYVPYDEAEVLMYPHMCTLANGSLVSPLYTQIPTTDSY-KSRANLTYPINVG 254
            :.||::..:...||:    :.::..:|                     ||| |...:..|||..
Human   139 IQFHIFTEDSLKPEF----DKQLRQWP---------------------DSYTKKFEHRIYPITF- 177

  Fly   255 RNIARLATNTHFIFACDIELYPSVGFVDQFLDMVARNHSVLALDPRQRRRVYPLPVFEIETGAKV 319
                                  |||...::..:         ..|...:|:: |||...:..:.:
Human   178 ----------------------SVGNPQEWKKL---------FKPCAAQRLF-LPVILKDVDSLL 210

  Fly   320 PVDKD-----------ELLALYRKQQAQVFHLKLCPTCHTIPGQEEWLNRTSRADDHLHVFSKA- 372
            .||.|           :||.|:...|...    :.|. |.|| :..|.:|.:|     |.|..:
Human   211 YVDTDVLFLRPVDDIWKLLRLFNSTQLAA----MAPE-HEIP-KIGWYSRFAR-----HPFYGSA 264

  Fly   373 -------------LRKWKFR--------AWEPFYVSDNTEPLFDE---RVTWEGQSNKRIQVSYY 413
                         :|..:|:        |||     |...||:.:   .:||..|....| :.|:
Human   265 GVNSGVMLMNLTRIRSTQFKNSMIPTGLAWE-----DMLYPLYQKYKNAITWGDQDLLNI-IFYF 323

  Fly   414 ---CSQVSVSQCN 423
               |..|...|.|
Human   324 NPECLYVFPCQWN 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11149	NP_608952.2	Glyco_transf_49	130..485	CDD:290607	53/273 (19%)
GXYLT2	NP_001073862.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..84
GXYLT2	NP_001073862.1	GT8_like_2	110..413	CDD:133052	53/273 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830