Protein Alignment CG11149 and large1

DIOPT Version :9

• Sequence 1: NP_608952.2
• Gene: CG11149 / 33800
• FlyBaseID: FBgn0031732
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001004537.1
• Gene: large1 / 446213
• ZFINID: ZDB-GENE-061204-1
• Length: 757
• Species: Danio rerio
• Alignment Length: 571
• Identity: 113/571 - (19%)
• Similarity: 185/571 - (32%)
• Gaps: 202/571 - (35%)

  Fly    14 LWPVLILFNVALLL-------------VWRNLQQAQKLAASSNTGGQKSVGLLLSNESNPSRFSA 65
            ||.|...|....:|             :|:|.:....|....|||    |.|||.:.....::..
Zfish   255 LWVVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGFNTG----VILLLLDRLRKLKWEQ 315

  Fly    66 NFHLANDQHPKIIRREDSARTKELRSLL--KCRDRSLRFERLQHGEFWLLQ-----NLVMGRKSR 123
            .:.|..:              :||.|:|  ...|:.:....::...|.:.|     |:.:...:|
Zfish   316 MWRLTAE--------------RELMSMLSTSLADQDIFNAVIKQNPFLVHQLPCYWNVQLSDHTR 366

  Fly   124 EVGCAESVTYTTNGDFTFFDNLEMVVSRWRAPVSFAIHTPGYDL--NTTLDAIRYVRN------- 179
            ...|.:.|:             ::.|..|.:|....:.....:.  |..|..:.|..|
Zfish   367 SEKCYKDVS-------------DLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELF 418

  Fly   180 -CLPESD----SIKDWVS--------------------FHVYFPNQHMPEYVP-YDEAEVL---- 214
             |..|:|    :::..:|                    .||||.:.   ||.| .|..:|.
Zfish   419 GCPSETDHNSENLQKTLSELDEDDPCYEFRRERFTVHRTHVYFLHY---EYEPTVDNTDVTLVAQ 480

  Fly   215 -------MYPHMCTLANGSLVSPLYTQIPTTDSY----------KSRANL----------TYPIN 252
                   |...:|....|.:...||........:          .||:|:          .||:|
Zfish   481 LSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRSNVGYHIVYKEGQFYPVN 545

  Fly   253 VGRNIARLATNTHFIFACDIELYPSVGFVDQFLDMVARNHSVLALDPRQRRRVYPLPVFE-IETG 316
            :.||:|....||.::|..||:..|..|..:..      ..||:.||....::...:|.|| :...
Zfish   546 LLRNVAMGQVNTPYMFLSDIDFLPMYGLYEYL------RKSVVQLDMGNTKKALVVPAFETLRYR 604

  Fly   317 AKVPVDKDELLALYRKQQAQVFHLKLCPTCHTIPGQEEWLNRTSRADDHLHVFSKA-----LRKW 376
            ...|..|.|||:  :.....:|..:                        .||::|.     ..||
Zfish   605 LSFPKSKAELLS--QLDMGTLFTFR------------------------YHVWTKGHAPTDFAKW 643

  Fly   377 K-----FRA-W----EPFYVSDNTEPLFDERVTWEGQSNKRIQVSYYCSQVSVSQCNLLLQNYAM 431
            :     :|. |    ||:.:.....|.:|.|....|. ||...:....:|
Zfish   644 RTATTPYRVQWEADFEPYVMVRRESPEYDRRFVGFGW-NKVAHIMELDAQ--------------- 692

  Fly   432 CLLDYEYHVLSPAFLVHSPGIKQSSKADSTRLQYAKEMTKFIKNKIEPEYR 482
               :||:.||..|:::|.|      .|.|.      ::|||..||   :||
Zfish   693 ---EYEFVVLPNAYMIHMP------HAPSF------DITKFRSNK---QYR 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11149	NP_608952.2	Glyco_transf_49	130..485	CDD:290607	87/435 (20%)
large1	NP_001004537.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..127
		RfaJ	137..>387	CDD:224359	30/162 (19%)
		GT8_LARGE_C	139..418	CDD:133053	34/193 (18%)
		Xylosyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461	139..414		34/189 (18%)
		Glucuronyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461	415..757		79/380 (21%)
		Glyco_transf_49	474..743	CDD:290607	67/318 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850