Protein Alignment CG11149 and Large1

DIOPT Version :9

• Sequence 1: NP_608952.2
• Gene: CG11149 / 33800
• FlyBaseID: FBgn0031732
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001304320.1
• Gene: Large1 / 16795
• MGIID: 1342270
• Length: 756
• Species: Mus musculus
• Alignment Length: 568
• Identity: 111/568 - (19%)
• Similarity: 181/568 - (31%)
• Gaps: 194/568 - (34%)

  Fly    14 LWPVLILFNVALLL-------------VWRNLQQAQKLAASSNTGGQKSVGLLLSNESNPSRFSA 65
            ||.|...|....:|             :|:|.:....|....|||    |.|||.::....::..
Mouse   254 LWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTG----VILLLLDKLRKMKWEQ 314

  Fly    66 NFHLANDQHPKIIRREDSARTKELRSLL--KCRDRSLRFERLQHGEFWLLQ-----NLVMGRKSR 123
            .:.|..:              :||..:|  ...|:.:....::...|.:.|     |:.:...:|
Mouse   315 MWRLTAE--------------RELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQLSDHTR 365

  Fly   124 EVGCAESVTYTTNGDFTFFDNLEMVVSRWRAPVSFAIHTPGYDL--NTTLDAIRYVRN------- 179
            ...|...|:             ::.|..|.:|....:.....:.  |..|..:.|..|
Mouse   366 SEQCYRDVS-------------DLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELF 417

  Fly   180 -CLPESD----SIKDWVS--------------------FHVYFPNQHMPEYVP-YDEAEVL---- 214
             |..|:|    :::..:|                    .|:||.:.   |:.| .|..:|.
Mouse   418 GCPSETDVNNENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHY---EFEPSADNTDVTLVAQ 479

  Fly   215 -------MYPHMCTLANGSLVSPLYTQIPTTDSY----------KSRANL----------TYPIN 252
                   |...:|....|.:...||........:          .||.|:          .||:|
Mouse   480 LSMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRQNVGYHIVYKEGQFYPVN 544

  Fly   253 VGRNIARLATNTHFIFACDIELYPSVGFVDQFLDMVARNHSVLALDPRQRRRVYPLPVFE-IETG 316
            :.||:|....:|.::|..||:..|..|..:..      ..||:.||....::...:|.|| :...
Mouse   545 LLRNVAMKHISTPYMFLSDIDFLPMYGLYEYL------RKSVIQLDLANTKKAMIVPAFETLRYR 603

  Fly   317 AKVPVDKDELLALYRKQQAQVFHLKLCPTCH-----------TIPGQEEWLNRTSRADDHLHVFS 370
            ...|..|.|||::........|...:....|           |.|.|.||     .||
Mouse   604 LSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYQVEW-----EAD------- 656

  Fly   371 KALRKWKFRAWEPFYVSDNTEPLFDERVTWEGQSNKRIQVSYYCSQVSVSQCNLLLQNYAMCLLD 435
                      :||:.|.....|.:|.|....|. ||...:....:|                  :
Mouse   657 ----------FEPYVVVRRDCPEYDRRFVGFGW-NKVAHIMELDAQ------------------E 692

  Fly   436 YEYHVLSPAFLVHSPGIKQSSKADSTRLQYAKEMTKFIKNKIEPEYRV 483
            ||:.||..|:::|.|      .|.|.      ::|||..||   :||:
Mouse   693 YEFTVLPNAYMIHMP------HAPSF------DITKFRSNK---QYRI 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11149	NP_608952.2	Glyco_transf_49	130..485	CDD:290607	86/432 (20%)
Large1	NP_001304320.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..64
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..108
		GT8_LARGE_C	138..417	CDD:133053	33/193 (17%)
		Xylosyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461	138..413		33/189 (17%)
		Glucuronyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461	414..756		78/377 (21%)
		Glyco_transf_49	473..742	CDD:372794	68/315 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D729091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850