Protein Alignment CG7236 and AURKA

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_016883523.1
• Gene: AURKA / 6790
• HGNCID: 11393
• Length: 437
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 84/348 - (24%)
• Similarity: 161/348 - (46%)
• Gaps: 64/348 - (18%)

  Fly    29 NEPDLVETRQYRPQGSSK----MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPA 89
            |.|:.....:.:.:.|.|    ::.:|....||:|.:|.||..|::::..::|:|...:::.:.|
Human   142 NNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA 206

  Fly    90 -IRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCEL-TVLHELERHPQGCPEHLTKQI 152
             :.....||:.:..:|:|||::.|...|....|::|:.|:..| ||..||::..: ..|..|...
Human   207 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATY 270

  Fly   153 CYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPEL 217
            ..:....::|||.:..:||||||||:||.:.|::|:.|||:: :.:|....|....|..|..||:
Human   271 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEM 334

  Fly   218 LVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKG 282
            :.| ..:...||:|::|.|..|.:.|:.  |..::..|                      |.:|.
Human   335 IEG-RMHDEKVDLWSLGVLCYEFLVGKP--PFEANTYQ----------------------ETYKR 374

  Fly   283 I-----TLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQ 342
            |     |.|         |.:...::      |.:.:.|..:|::|....::.:|.:..
Human   375 ISRVEFTFP---------DFVTEGAR------DLISRLLKHNPSQRPMLREVLEHPWIT------ 418

  Fly   343 RELEHVNSLEAANLRQQQLASQQ 365
                 .||.:.:|.:.::.||:|
Human   419 -----ANSSKPSNCQNKESASKQ 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	74/293 (25%)
		Pkinase	50..335	CDD:278497	74/291 (25%)
AURKA	XP_016883523.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910