DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and TBC1D22B

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_060242.2	Gene:	TBC1D22B / 55633	HGNCID:	21602	Length:	505	Species:	Homo sapiens

Alignment Length:	156	Identity:	34/156 - (21%)
Similarity:	57/156 - (36%)	Gaps:	41/156 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 KMPAKSQ-----QNP-----LTIDFLKK--CLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVN 349
            |:|...|     |:|     ||.:|:|:  .::..|.|.      .|.|.|.::.....:...:.
Human    15 KLPGSIQPVYGAQHPPLDPRLTKNFIKERSKVNTVPLKN------KKASSFHEFARNTSDAWDIG 73

  Fly   350 SLEAANLRQQ--QLASQQFMLATAAQQLQTG-----------------PAQAAAIAAARDKSKTS 395
            ..|..:....  |..:.:..||||||.|:..                 ||....|.::.|...:.
Human    74 DDEEEDFSSPSFQTLNSKVALATAAQVLENHSKLRVKPERSQSTTSDVPANYKVIKSSSDAQLSR 138

  Fly   396 NTSLPLLPSTQHHHHPHQDYVKLQPL 421
            |:|...|.:..|    .|..:.|:|:
Human   139 NSSDTCLRNPLH----KQQSLPLRPI 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	13/49 (27%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	13/49 (27%)
TBC1D22B	NP_060242.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	105..146		6/40 (15%)
TBC1D22B	NP_060242.2	TBC	207..457	CDD:214540
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910