DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and CG1951

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_651655.1	Gene:	CG1951 / 43423	FlyBaseID:	FBgn0039623	Length:	835	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	83/382 - (21%)
Similarity:	136/382 - (35%)	Gaps:	103/382 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 NSFLYRLIQKIQVCNE--PDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVY----KCRDRETG 73
            |.|....:|.:...:.  |....||:|        :..|::...|.|....||    |...:|..
  Fly     5 NKFYSSAVQTVSTLSGVLPGNNVTREY--------EVLEQVCTAGVGLMWKVYNGHKKSTKQEVS 61

  Fly    74 ALVAVKRFVE--SEDDPAIRKIALRE-IRLLKNLKHPNLVSLLEVFRRKRRLHLVFE----FCEL 131
            ..|..|:.:|  |:||.......||. ::.|..::||:::::.......|. .|.|.    |..|
  Fly    62 VFVFEKKSLERWSKDDRETMLETLRRGVQQLTKIRHPHVLTVQHPLEESRD-SLAFATEPVFASL 125

  Fly   132 T-----------VLHELE-RHPQGCPEHLTKQICYQTLLGVAYCHKQG-CLHRDIKPENILLTAQ 183
            .           .|:::| ||.           ..|...|:.:.|:.. .:||:|..|.|::...
  Fly   126 ANVVGDNVRSEKKLYDVEIRHG-----------LLQLFDGLQFLHQDAKIVHRNISAETIVINKN 179

  Fly   184 GQVKLCDFGFARMLSPGENYTDYVATRW------------------YRAPELLVGDTQYGTP-VD 229
            ...||..|.|.....|..:.|.:    |                  |.||||.:...  .|| .|
  Fly   180 RSWKLFGFDFCIANQPATDGTPH----WPFREYTTSLHVLAQPSLEYTAPELALNSV--NTPDSD 238

  Fly   230 VWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPL 294
            ::::|.|...:..|:.|....||...   .|:...||        .|.:|        ||.
  Fly   239 LFSLGVLIFTIYAGKPLKMFGSDYSS---FRRYANDL--------NQRKY--------PPM---- 280

  Fly   295 EDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSL 351
             :.:|::..::      ||..|......|....:|.:.:||.|...|  .|.:::||
  Fly   281 -NAVPSELTES------LKALLHPSANLRPKLHELKQIAYFQDVGVK--TLSYLDSL 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	69/329 (21%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	69/327 (21%)
CG1951	NP_651655.1	Pkinase	31..314	CDD:278497	70/338 (21%)
		PK_SCY1_like	37..316	CDD:270913	70/326 (21%)
		HEAT repeat	396..425	CDD:293787
		HEAT repeat	435..465	CDD:293787
		HEAT repeat	474..501	CDD:293787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910