Protein Alignment CG7236 and MAK

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001229886.1
• Gene: MAK / 4117
• HGNCID: 6816
• Length: 648
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 135/413 - (32%)
• Similarity: 205/413 - (49%)
• Gaps: 50/413 - (12%)

  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVE---SEDDPAIRKIALREIRLLKNLKHPN 108
            |:||..:.:||:|:||.|...:..|:|.|||:||...   |.|:    .:.|||::.||.|.|.|
Human     1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDE----CMNLREVKSLKKLNHAN 61

  Fly   109 LVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDI 173
            ::.|.||.|....|:.:||:.:..:...::...:..||.:.:.|.||.|.|:|:.||.|..|||:
Human    62 VIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDM 126

  Fly   174 KPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFA 238
            ||||:|......||:.|||.||.|.....|||||:||||||||:|:..:.|.:|:||||:|.:.|
Human   127 KPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMA 191

  Fly   239 ELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLP----------VPPTLEP 293
            ||.....|:||.|:||:::.|.:.||  .|:      ::::.:|..|.          ||..|:.
Human   192 ELYMLRPLFPGTSEVDEIFKICQVLG--TPK------KSDWPEGYQLASSMNFRFPQCVPINLKT 248

  Fly   294 LEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSLEAANLRQ 358
            |   :|..|.:   .|..:.:.|:.||.||.:..:..||.||...........|:.|.::.|.:.
Human   249 L---IPNASNE---AIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSLNKQL 307

  Fly   359 QQLASQQFMLATAAQQLQTGPAQAAAIAAARDKSKTS-----------NTSLPLLPSTQHHHHPH 412
            |.|.|:..::....:.|.....|    ...:.:.|||           |.|:...|..|....|.
Human   308 QPLESKPSLVEVEPKPLPDIIDQ----VVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQSQEKPP 368

  Fly   413 Q----DYVKLQPLNKNANLLHRT 431
            |    ..||..|...|..|.|::
Human   369 QTLFPSIVKNMPTKPNGTLSHKS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	109/299 (36%)
		Pkinase	50..335	CDD:278497	108/297 (36%)
MAK	NP_001229886.1	STKc_MAK_like	4..284	CDD:270824	108/297 (36%)
		S_TKc	4..284	CDD:214567	108/297 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910