Protein Alignment CG7236 and Cdk12

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 125/396 - (31%)
• Similarity: 187/396 - (47%)
• Gaps: 70/396 - (17%)

  Fly    23 QKIQVCNEPDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDD 87
            |:..:.|..|  .....|..|...:|.:|.::::|||:||.|||.||..|..:||:|:.....:.
  Fly   779 QRPVILNRRD--SRNNVRDWGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEK 841

  Fly    88 PAIRKIALREIRLLKNLKHPNLVSLLEV---------FRR-KRRLHLVFEFCELTVLHELERHPQ 142
            ......|:|||::|:.|.|.|:|:|.|:         ||: |...:||||:.:..::..||....
  Fly   842 EGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMV 906

  Fly   143 GCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGEN---YT 204
            ...|.....|..|.|.|:.||||:..||||||..|||:..:|:|||.|||.||:.:..:.   ||
  Fly   907 DFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYT 971

  Fly   205 DYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPR 269
            :.|.|.|||.||||:|:.:||..:|||:.||:..||.....|:...:::.||..|.|..|..:|.
  Fly   972 NKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPA 1036

  Fly   270 HIQIFGQNEYFKGITLPVPPTLEPLE----------DKMPAKSQQNPLTIDFLKKCLDKDPTKRW 324
                    .:...|.||:..||:..:          :.|||.:      :|.|.|.||.||.||.
  Fly  1037 --------VWPNVIKLPLFHTLKQKKTHRRRLREDFEFMPAPA------LDLLDKMLDLDPDKRI 1087

  Fly   325 SCEKLTKHSYFDDYIAKQRELEHVNSLEA---------------ANLRQQQLASQQFML------ 368
            :.|...:..:          |..:|..|.               :..|::|:..||..|
  Fly  1088 TAEDALRSPW----------LRKINPDEMPTPQLPTWQDCHELWSKKRRRQMREQQESLPPTVIA 1142

  Fly   369 ATAAQQ 374
            :|..||
  Fly  1143 STKYQQ 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	109/309 (35%)
		Pkinase	50..335	CDD:278497	108/307 (35%)
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	110/325 (34%)
		S_TKc	804..1098	CDD:214567	108/317 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030