DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and stk4

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_989249.1	Gene:	stk4 / 394860	XenbaseID:	XB-GENE-955920	Length:	485	Species:	Xenopus tropicalis

Alignment Length:	360	Identity:	98/360 - (27%)
Similarity:	166/360 - (46%)	Gaps:	65/360 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IQKIQVCNEPDLVETRQYRPQGSSKMDR-----YEKLSRLGEGSYGVVYKCRDRETGALVAVKRF 81
            ::.:|:.|.|    .|..:......:::     ::.|.:|||||||.|||...:||..:||:|:.
Frog     1 METVQLRNNP----RRHLKKLSEESLNKQPEEVFDVLEKLGEGSYGSVYKASHKETSQIVAIKQI 61

  Fly    82 -VESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELER-HPQGC 144
             |||:    :::| ::||.:::.....::|.....:.:...|.:|.|||....:.::.| ..|..
Frog    62 PVESD----LQEI-IKEIAIMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSISDIIRLRKQTL 121

  Fly   145 PEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVAT 209
            .|..|..|...||.|:.|.|....:|||||..||||.::|..||.|||.|..|      ||.:|.
Frog   122 KEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGTAKLADFGVAGQL------TDTMAK 180

  Fly   210 R-------WYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLL 267
            |       ::.||| ::.:..|....|:|::|....|:..|:
Frog   181 RNTVIGTPFWMAPE-VIQEIGYNCVADIWSLGITAIEMAEGK----------------------- 221

  Fly   268 PRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKH 332
            |.:.:|......|...:.| |||..  :.::.:|.     .:||:..||.|:|..|.|..:|.:|
Frog   222 PPYAEIHPMRAIFMIPSNP-PPTFR--KPELWSKD-----FVDFINLCLVKNPELRSSATELLQH 278

  Fly   333 SYFDDYIAK-QRELEH-VNSLEAANLRQQQLASQQ 365
            .:..  .|| :..|.| :|..:.|.|::.:|..::
Frog   279 PFIK--TAKGESILRHLINEAQDAKLKRTELKQRE 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	86/300 (29%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	86/293 (29%)
stk4	NP_989249.1	STKc_MST1_2	26..281	CDD:132943	86/297 (29%)
stk4	NP_989249.1	Mst1_SARAH	431..478	CDD:314497
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910