Protein Alignment CG7236 and Cdkl4

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001028615.1
• Gene: Cdkl4 / 381113
• MGIID: 3587025
• Length: 342
• Species: Mus musculus
• Alignment Length: 392
• Identity: 193/392 - (49%)
• Similarity: 266/392 - (67%)
• Gaps: 50/392 - (12%)

  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVS 111
            |::||||:::||||||||:|||::.:|.:||:|:|||||||..:|||||||||:||.|||||||:
Mouse     1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHPNLVN 65

  Fly   112 LLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPE 176
            |:|||||||::|||||:|:.|:|:||||:|.|..:.:.|.:.:|||..:.:|||..|:|||:|||
Mouse    66 LIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKPE 130

  Fly   177 NILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELV 241
            |||:|.||.:|:|||||||:|.||:.||||||||||||||||||||:||:.|||||:||:||||:
Mouse   131 NILITKQGMIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTKYGSSVDVWAVGCVFAELL 195

  Fly   242 RGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNP 306
            .|:.||||:|||||||||.:|||.|:|||..||..|::|:||::|.|..:|.||:|.   |...|
Mouse   196 TGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFRSNQFFRGISIPEPEDMETLEEKF---SNVQP 257

  Fly   307 LTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSLEAANLRQQQLASQQFMLATA 371
            :.:.|:|.||..:|.:|.:|.:|...:||:.:  ::.:::.....|..:.|:||
Mouse   258 VALSFMKGCLKMNPDERLTCAQLLDSAYFESF--QEDQMKRKARSEGRSRRRQQ----------- 309

  Fly   372 AQQLQTGPAQAAAIAAARDKSKTSNTSLPLLPSTQHHHHPHQDYVKLQPLNKNANLLHRTEHHLP 436
                                    |..|||:|.:  |..|..|..|        .::.....|||
Mouse   310 ------------------------NQLLPLIPGS--HISPTPDGRK--------QVVQLKFDHLP 340

  Fly   437 TI 438
            .|
Mouse   341 NI 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	173/286 (60%)
		Pkinase	50..335	CDD:278497	173/284 (61%)
Cdkl4	NP_001028615.1	STKc_CDKL1_4	2..286	CDD:270837	173/286 (60%)
		[NKR]KIAxRE	45..51		5/5 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..328		12/69 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	415	1.000	Domainoid score	I665
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	420	1.000	Inparanoid score	I1778
Isobase	1	0.950	-	0	Normalized mean entropy	S801
OMA	1	1.010	-	-		QHG52261
OrthoDB	1	1.010	-	-		D398098at2759
OrthoFinder	1	1.000	-	-		FOG0004639
OrthoInspector	1	1.000	-	-		otm43978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.030