DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7236 and Cdk4

DIOPT Version :9

Sequence 1:NP_608950.3 Gene:CG7236 / 33798 FlyBaseID:FBgn0031730 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_001286493.1 Gene:Cdk4 / 36854 FlyBaseID:FBgn0016131 Length:317 Species:Drosophila melanogaster


Alignment Length:325 Identity:103/325 - (31%)
Similarity:156/325 - (48%) Gaps:43/325 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 RQYRPQGSSKMDR--------YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKI 93
            ||.:.|..|:..:        |::|:.:|||:||.||:.||..||.:||:|:...|.::..:...
  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69

  Fly    94 ALREIRLLKNL---KHPNLVSLLEVFRRKRR-----LHLVFEFCELTVLHELERHPQ-GCPEHLT 149
            .||||.|||.|   .|.|:|.|.||.:...|     :.||||..|..:...::|.|: |......
  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134

  Fly   150 KQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRA 214
            :::..:.|.||.:.|....:|||:||:|:|:::||.:|:.|||.|:........|..|.|.||||
  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRA 199

  Fly   215 PELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEY 279
            ||:|:.. .|.:.||:|:..|:..|:....||:||.|:.:||..|.:..|  .|...|       
  Fly   200 PEVLLAQ-PYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTG--RPTEQQ------- 254

  Fly   280 FKGITLPVPPTLEPLEDKMPAKSQQNPLTI---------DFLKKCLDKDPTKRWSCEKLTKHSYF 335
                   .|.|:....:..|.:..:.|...         |.|.|.|..|...|.|.....:|.||
  Fly   255 -------WPQTISVALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312

  Fly   336  335
              Fly   313  312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7236NP_608950.3 STKc_CDKL1_4 48..335 CDD:270837 97/312 (31%)
Pkinase 50..335 CDD:278497 97/302 (32%)
Cdk4NP_001286493.1 STKc_CDK4_6_like 26..312 CDD:270831 97/302 (32%)
S_TKc 26..312 CDD:214567 97/302 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442457
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24056
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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