DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and Cdk2

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_006240840.1	Gene:	Cdk2 / 362817	RGDID:	70486	Length:	346	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	121/355 - (34%)
Similarity:	178/355 - (50%)	Gaps:	83/355 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVS 111
            |:.::|:.::|||:||||||.:::.||.:||:|:.....:...:...|:|||.|||.|.|||:|.
  Rat     1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVK 65

  Fly   112 LLEVFRRKRRLHLVFEFCELTVLH-ELERHPQ-----GCPEHLTKQICYQTLLGVAYCHKQGCLH 170
            ||:|...:.:|:|||||     || :|::...     |.|..|.|...:|.|.|:|:||....||
  Rat    66 LLDVIHTENKLYLVFEF-----LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125

  Fly   171 RDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIG 234
            ||:||:|:|:.|:|.:||.|||.||... |...||..|.|.||||||:|:|...|.|.||:|::|
  Rat   126 RDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLG 190

  Fly   235 CLFAEL------------------------------------------------VRGEALWPGRS 251
            |:|||:                                                |...||:||.|
  Rat   191 CIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSTPYPVTRRALFPGDS 255

  Fly   252 DVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQN------PLTID 310
            ::|||:.|.:|||  .|..:       .:.|:|     ::...:...|..::|:      ||..|
  Rat   256 EIDQLFRIFRTLG--TPDEV-------VWPGVT-----SMPDYKPSFPKWARQDFSKVVPPLDED 306

  Fly   311 ---FLKKCLDKDPTKRWSCEKLTKHSYFDD 337
               .|.:.|..||.||.|.:....|.:|.|
  Rat   307 GRSLLSQMLHYDPNKRISAKAALAHPFFQD 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	118/350 (34%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	118/348 (34%)
Cdk2	XP_006240840.1	STKc_CDK2_3	3..334	CDD:270844	118/349 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910