Protein Alignment CG7236 and NEK5

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001352481.1
• Gene: NEK5 / 341676
• HGNCID: 7748
• Length: 832
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 97/400 - (24%)
• Similarity: 160/400 - (40%)
• Gaps: 76/400 - (19%)

  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIA-LREIRLLKNLKHPNLV 110
            ||:|:.:..:|:|::|..|..:.:.......:|. :..|..|...|.| .:|:.||:.:||||:|
Human     1 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKE-INFEKMPIQEKEASKKEVILLEKMKHPNIV 64

  Fly   111 SLLEVFRRKRRLHLVFEFCELTVLHELERHPQGC--PEHLTKQICYQTLLGVAYCHKQGCLHRDI 173
            :....|:...||.:|.|:|:...|.:.....:|.  .|........|..||:.:.|.:..|||||
Human    65 AFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDI 129

  Fly   174 KPENILLTAQGQV-KLCDFGFARMLSPG-ENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCL 236
            |.:||.|:..|.| ||.|||.||:|:.. |.....:.|.:|.:|| :..:..|....|:|::||:
Human   130 KAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPE-ICQNKPYNNKTDIWSLGCV 193

  Fly   237 FAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPP----TLEPLEDK 297
            ..||...:..:.| :::.||.|      .:...|.             .|:.|    .|..|
Human   194 LYELCTLKHPFEG-NNLQQLVL------KICQAHF-------------APISPGFSRELHSL--- 235

  Fly   298 MPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSLEAANLRQQQLA 362
                          :.:.....|..|.|...:.|..:.::.|.|....|.:         |::.:
Human   236 --------------ISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPEVI---------QEEFS 277

  Fly   363 SQQFMLATAAQQLQTGP-AQAAAIAAARDKSKTSNTSLPLLPSTQHHHHPHQDYVKLQPLNKNAN 426
            ......|.|......|. .|...|...|.:.|.                |.:..:.: |:.:||
Human   278 HMLICRAGAPASRHAGKVVQKCKIQKVRFQGKC----------------PPRSRISV-PIKRNA- 324

  Fly   427 LLHRTEHHLP 436
            :|||.|...|
Human   325 ILHRNEWRPP 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	76/295 (26%)
		Pkinase	50..335	CDD:278497	75/293 (26%)
NEK5	NP_001352481.1	STKc_Nek5	3..259	CDD:173765	75/294 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910