DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and Tbck

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001156927.1	Gene:	Tbck / 271981	MGIID:	2445052	Length:	893	Species:	Mus musculus

Alignment Length:	257	Identity:	72/257 - (28%)
Similarity:	112/257 - (43%)	Gaps:	34/257 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 LREIRLLKNLKHPNLVSLLEVFRRK-RRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLL 158
            |...::||.:.||.|...:::.|.| .||.:|.|.||.: |.:|.|..:.........|.|:.|.
Mouse    39 LGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERS-LEDLLRERKPVSHSTVLCIAYEVLE 102

  Fly   159 GVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLV---- 219
            |:.|.:|.|.:||.:.|.||||..:|.:||..||...|.:.|::....:....|.|||::.
Mouse   103 GLHYLNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIP 167

  Fly   220 GDTQY---------GTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFG 275
            ..|.:         |...|||::|.:..||..|..|:.. .||.:......||| .:...|.:..
Mouse   168 KTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQS-LDVSERVKFLLTLG-CVDDTIIVLA 230

  Fly   276 QNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDD 337
            :......|...:|..:                 |:.|||||...|:||.:.::|.|...|.:
Mouse   231 EEHGCLDIIKELPENV-----------------INILKKCLTFHPSKRPTPDELMKDQVFSE 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	71/253 (28%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	71/253 (28%)
Tbck	NP_001156927.1	S_TKc	43..273	CDD:214567	70/249 (28%)
		PKc_like	43..271	CDD:304357	70/247 (28%)
		TBC	467..671	CDD:214540
		RHOD	771..882	CDD:294087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910