DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and wee1

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_587933.1	Gene:	wee1 / 2539123	PomBaseID:	SPCC18B5.03	Length:	877	Species:	Schizosaccharomyces pombe

Alignment Length:	241	Identity:	64/241 - (26%)
Similarity:	108/241 - (44%)	Gaps:	36/241 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SSSFYLPQSLQNSFLYRLIQKIQVCNEPDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVYKCR 68
            ||||.|      ||             |..:.:.:.....|..:.|:..::.||.|.:..|::..
pombe   539 SSSFTL------SF-------------PSALTSSKVSSSTSHLLTRFRNVTLLGSGEFSEVFQVE 584

  Fly    69 DR-ETGALVAVKRFVESEDDPAIRKIALREIRLLKNLK-HPNLVSLLEVFRRKRRLHLVFEFCEL 131
            |. |.....|||:.......|..|...|:|:.:.:.|| |.::|.|::.:.....|::..|.||.
pombe   585 DPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHIVELMDSWEHGGFLYMQVELCEN 649

  Fly   132 TVLHE-LERHPQ--GCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGF 193
            ..|.. ||...|  ...|....:|..:..||:.:.|.:..:|.|:||.|:::|.:|.:|:.|||.
pombe   650 GSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGM 714

  Fly   194 ARM--LSPG---ENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIG 234
            |.:  :..|   |...:|:      |||:|.... |..|.|::::|
pombe   715 ASVWPVPRGMEREGDCEYI------APEVLANHL-YDKPADIFSLG 753

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	55/197 (28%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	54/195 (28%)
wee1	NP_587933.1	PTKc_Wee1_fungi	565..838	CDD:270954	55/196 (28%)
wee1	NP_587933.1	Pkinase	566..836	CDD:278497	54/195 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910