DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7236 and HIPK1

DIOPT Version :9

Sequence 1:NP_608950.3 Gene:CG7236 / 33798 FlyBaseID:FBgn0031730 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_001356735.1 Gene:HIPK1 / 204851 HGNCID:19006 Length:1210 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7236NP_608950.3 STKc_CDKL1_4 48..335 CDD:270837
Pkinase 50..335 CDD:278497
HIPK1NP_001356735.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1084..1103
STKc_HIPK1 174..528 CDD:271130
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 835..856
Nuclear localization signal 1 (NLS1). /evidence=ECO:0000250 844..847
Interaction with TP53. /evidence=ECO:0000269|PubMed:12702766 885..1093
Required for localization to nuclear speckles. /evidence=ECO:0000250 891..998
SUMO interaction motifs (SIM), required for nuclear localization and kinase activity. /evidence=ECO:0000250 902..926
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 909..974
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1046..1069
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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