Protein Alignment CG7236 and HIPK4

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_006723099.1
• Gene: HIPK4 / 147746
• HGNCID: 19007
• Length: 619
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 112/399 - (28%)
• Similarity: 178/399 - (44%)
• Gaps: 69/399 - (17%)

  Fly    45 SKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLK---- 105
            |:.|.|:.:..||:|::|.|.|...|.||.:||:|..   ::|....:|...|::||..::
Human     6 SETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKIL---KNDAYRNRIIKNELKLLHCMRGLDP 67

  Fly   106 -HPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCP---EHLTKQICYQTLLGVAYCHKQ 166
             ..:::..||.|....:.:||||..|.. |.|.::.....|   .|: :.:..|.|..:|...:.
Human    68 EEAHVIRFLEFFHDALKFYLVFELLEQN-LFEFQKENNFAPLPARHI-RTVTLQVLTALARLKEL 130

  Fly   167 GCLHRDIKPENILLTAQG----QVKLCDFGFARMLSPGENYTD-YVATRWYRAPELLVGDTQYGT 226
            ..:|.|:|||||:|..|.    :||:.|||.|.:.|......: |:.:|:|||||:|:| ..:..
Human   131 AIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLG-LPFCE 194

  Fly   227 PVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPR-HI--------QIFGQNEYFKG 282
            .||||::||:.|||..|..|:||.::.||:..|.:|.|  ||: |:        ..|.:|
Human   195 KVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQG--LPKPHLLHAACKAHHFFKRN----- 252

  Fly   283 ITLPVPPTLEPLEDKMP----AKSQQNPL-TIDFLKKCLDKDPTKRWSC----------EKLTKH 332
               |.|....|.:.|..    |:::..|| ...::.|.||:..|.....          |.|.:|
Human   253 ---PHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEH 314

  Fly   333 SYFDDYIAKQREL----EHVNSLEAANLR-----QQQLAS-------QQFMLATAAQQLQTGPAQ 381
            :.....:...:.:    .|.....:|.||     .|||.|       .|..|.:....||.....
Human   315 ADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKP 379

  Fly   382 AAAIAAARD 390
            ...:.||.|
Human   380 PTPVVAAED 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	96/323 (30%)
		Pkinase	50..335	CDD:278497	95/321 (30%)
HIPK4	XP_006723099.1	PKc_like	11..347	CDD:304357	99/351 (28%)
		S_TKc	11..347	CDD:214567	99/351 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910