DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and AgaP_AGAP010551

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_314524.4	Gene:	AgaP_AGAP010551 / 1275286	VectorBaseID:	AGAP010551	Length:	1418	Species:	Anopheles gambiae

Alignment Length:	356	Identity:	90/356 - (25%)
Similarity:	156/356 - (43%)	Gaps:	88/356 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RLIQKIQVCNEPDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKR-FVE 83
            |:...|::..:|               .|.::.:..||:|::|.|||.::|||..|.|.|. .:|
Mosquito    22 RIFNNIRMDTDP---------------ADFWDMIGELGDGAFGKVYKAQNRETKQLAAAKMCTLE 71

  Fly    84 SEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCE----LTVLHELERHPQGC 144
            .|::.:...:   ||.:|..:||||:|.|.|.:....:|.::.|:|:    .:::.|||:   ..
Mosquito    72 DEENLSDHMV---EIDILSEIKHPNIVGLYEAYSIDDKLWMLIEYCDGGALDSIMVELEK---PL 130

  Fly   145 PEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGF-ARMLSPGENYTDYVA 208
            .|.....:|.....|:.:.||...:|||:|..|:|||..|.|||.|||. |:.....:.:..::.
Mosquito   131 TEAQIAYVCKHMCAGLNHLHKNKVIHRDLKAGNVLLTMDGGVKLADFGVSAKNKHTMQKHDTFIG 195

  Fly   209 TRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQI 273
            |.::.||||::.:|                        ||..|::..:.::.|
Mosquito   196 TPYWMAPELVLCET------------------------WPPNSEMSPMRVLLK------------ 224

  Fly   274 FGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSY---- 334
                     |....||.|:     .|:|..::  ..|||.:.|.|||.:|.|.|.|...|:
Mosquito   225 ---------IQKSEPPKLD-----QPSKWSKH--FNDFLARALVKDPQQRPSTEVLMGLSFISGN 273

  Fly   335 FDDYIAKQRELEHVNSLEAANLRQQQLASQQ 365
            .|....|...||:     .|::.:::|..::
Mosquito   274 LDSKPIKDLLLEY-----KADVVEEELVDEE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	81/296 (27%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	80/294 (27%)
AgaP_AGAP010551	XP_314524.4	PKc_like	31..285	CDD:304357	84/326 (26%)
		S_TKc	37..270	CDD:214567	80/290 (28%)
		PKK	961..1093	CDD:289257
		PKK	1127..1267	CDD:289257
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910