DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and AgaP_AGAP002142

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_308053.4	Gene:	AgaP_AGAP002142 / 1269416	VectorBaseID:	AGAP002142	Length:	810	Species:	Anopheles gambiae

Alignment Length:	339	Identity:	71/339 - (20%)
Similarity:	119/339 - (35%)	Gaps:	117/339 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 GVVYKCRDRETGALVAVKRFVESED------DPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKR 120
            |||...:.|....|.......||.|      :|.:..:|    .||.|..:.:...||..::
Mosquito    88 GVVQLTKIRHPQVLTVQHAMEESRDTIAFATEPVVASLA----NLLGNTTNVSNTGLLAEYK--- 145

  Fly   121 RLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQ-GCLHRDIKPENILLTAQG 184
                         |.|.:          ||...::.:.|:.:.|.: ..:||.:..|||::..||
Mosquito   146 -------------LSEFD----------TKFGIFELIKGIRFLHDEVQLVHRHLCTENIIVNKQG 187

  Fly   185 QVKLCDFGF-----------------ARML-SPGENYTDYVATRWYRAPELLVGDTQYGTPVDVW 231
            ..||..|||                 :|:| :||..:|         ||||::.:|
Mosquito   188 VWKLFGFGFCWSKRAPGTPVGNHPFKSRLLGNPGSKWT---------APELILENT--------- 234

  Fly   232 AIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLED 296
               |:....:......|.......||                 |..:....::...||.|..:.:
Mosquito   235 ---CILIYTIYTRENIPSPDASSDLY-----------------GYKQSVTKLSNQGPPKLTVIPE 279

  Fly   297 KMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF-DDYIAKQRELEHVNSLEAA----NL 356
            .:.::          :||.|..:|..|.:.:.||:.||| |.|:      :.::|||..    ||
Mosquito   280 SLRSE----------VKKMLSVNPQARPTLQSLTQISYFCDQYV------QCLDSLETLFPKDNL 328

  Fly   357 RQQQLASQQFMLAT 370
            .:.:...:   |||
Mosquito   329 EKSEFYKR---LAT 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	59/297 (20%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	59/297 (20%)
AgaP_AGAP002142	XP_308053.4	Pkinase	31..308	CDD:278497	59/297 (20%)
		PK_SCY1_like	37..310	CDD:270913	61/299 (20%)
		HEAT repeat	429..459	CDD:293787
		HEAT repeat	468..495	CDD:293787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910