Protein Alignment CG7236 and Cdk4

DIOPT Version :9

• Sequence 1: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_034000.1
• Gene: Cdk4 / 12567
• MGIID: 88357
• Length: 303
• Species: Mus musculus
• Alignment Length: 304
• Identity: 109/304 - (35%)
• Similarity: 164/304 - (53%)
• Gaps: 32/304 - (10%)

  Fly    49 RYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPA--------IRKIALREIRLLKNLK 105
            |||.::.:|.|:||.|||.||..:|..||:|.........|        :|::||  :|.|:..:
Mouse     5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVAL--LRRLEAFE 67

  Fly   106 HPNLVSLLEVFRRKR-----RLHLVFEFCELTVLHELER-HPQGCPEHLTKQICYQTLLGVAYCH 164
            |||:|.|::|....|     ::.||||..:..:...|:: .|.|.|....|.:..|.|.|:.:.|
Mouse    68 HPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLH 132

  Fly   165 KQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVD 229
            ....:|||:||||||:|:.|.|||.|||.||:.|.....|..|.|.||||||:|:..| |.||||
Mouse   133 ANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVD 196

  Fly   230 VWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLP----VPPT 290
            :|::||:|||:.|.:.|:.|.|:.|||..|...:|  ||      .::::.:.::||    .|..
Mouse   197 MWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIG--LP------PEDDWPREVSLPRGAFAPRG 253

  Fly   291 LEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSY 334
            ..|::..:|...:..   ...|.:.|..:|.||.|..:..:|||
Mouse   254 PRPVQSVVPEMEESG---AQLLLEMLTFNPHKRISAFRALQHSY 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	109/304 (36%)
		Pkinase	50..335	CDD:278497	108/303 (36%)
Cdk4	NP_034000.1	STKc_CDK4	5..295	CDD:143368	109/304 (36%)
		Required for binding D-type cyclins. /evidence=ECO:0000250	50..56		0/5 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910