DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and Cdk20

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_444410.1	Gene:	Cdk20 / 105278	MGIID:	2145349	Length:	346	Species:	Mus musculus

Alignment Length:	295	Identity:	119/295 - (40%)
Similarity:	166/295 - (56%)	Gaps:	13/295 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPN-LV 110
            ||:|..|.|:|||::|:|:|.:..|||.:||:|:......:..|...|||||:.|:.::... :|
Mouse     1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVV 65

  Fly   111 SLLEVFRRKRRLHLVFEFCELTVLHELERHPQG--CPEHLTKQICYQTLLGVAYCHKQGCLHRDI 173
            .|..||.......|.|||. |:.|.|:.||.|.  .|..: |......|.|||:||....:|||:
Mouse    66 QLKAVFPHGAGFVLAFEFM-LSDLAEVVRHAQRPLAPAQV-KSYLQMLLKGVAFCHANNIVHRDL 128

  Fly   174 KPENILLTAQGQVKLCDFGFARMLSP--GENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCL 236
            ||.|:|::|.||:|:.|||.||:.||  |..||..||||||||||||.|..||...||:||:||:
Mouse   129 KPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCI 193

  Fly   237 FAELVRGEALWPGRSDVDQLYLIRKTLGDLLPR-HIQIFGQNEYFKGITLPVPPTLEPLEDKMPA 300
            ..||:.|..|:||.:|::||..:.:.||...|| ..:|....:|.|.......|.  |||:.:|.
Mouse   194 MGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKISFKEQAPV--PLEEVLPD 256

  Fly   301 KSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF 335
            .|   |..:|.|.:.|...|.:|.:..:...|.||
Mouse   257 AS---PQALDLLGQFLLYPPRQRIAASQALLHQYF 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	116/292 (40%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	115/290 (40%)
Cdk20	NP_444410.1	STKc_CCRK	3..289	CDD:270826	117/293 (40%)
Cdk20	NP_444410.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	298..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910