DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and wee2

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001096499.1	Gene:	wee2 / 100125126	XenbaseID:	XB-GENE-5560750	Length:	562	Species:	Xenopus tropicalis

Alignment Length:	399	Identity:	100/399 - (25%)
Similarity:	162/399 - (40%)	Gaps:	88/399 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PDLVETRQYRPQGSSKMDRYE----KLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIR 91
            |.:.:::::..:.::.:.||:    ::.::|.|.:|.|:||..|..|...|:||..:........
Frog   194 PAVFQSKRFVLRETNMVSRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYAIKRSKKPLAGSTDE 258

  Fly    92 KIALREIRLLKNL-KHPNLVSLLEVFRRKRRLHLVFEFCELTVLHEL--ERHPQG--CPEHLTKQ 151
            ::||||:.....| .||::|.....:.....:.:..|:|....|.:|  |...:|  .||...|:
Frog   259 QLALREVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCNGGSLQDLIMENKKEGRFVPEQELKE 323

  Fly   152 ICYQTLLGVAYCHKQGCLHRDIKPENILL----TAQGQ---------------VKLCDFG-FARM 196
            |..|..:|:.|.|..|.:|.||||.||.:    |..||               .|:.|.| ...:
Frog   324 ILLQVSMGLKYIHSSGLVHMDIKPSNIFICRKQTEVGQDESDGEDDLSSASVLYKIGDLGHVTSI 388

  Fly   197 LSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRK 261
            |:|.....|   :| :.|.|:|..|.:.....|::|:| |...|..|....|  .:.|..:.|||
Frog   389 LNPQVEEGD---SR-FLANEILQEDYRQLPKADIFALG-LTITLAAGAGPLP--CNEDSWHHIRK 446

  Fly   262 TLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSC 326
              |:|  .||              |.|.|               |..:..||..:..||..|...
Frog   447 --GNL--PHI--------------PQPLT---------------PAFLALLKLLVHPDPVMRPPA 478

  Fly   327 EKLTKHSYFDDYIAKQRELEHVNSLEAANLRQQQLASQQFMLATAAQQLQTGPAQAAAIAAARDK 391
            ..|.|:|.....:.|..:|            |:||..::|..|...::|     :||.:|....|
Frog   479 VSLAKNSLLRRCVGKAAQL------------QKQLNVEKFKTAMLEREL-----KAAKLAHGSGK 526

  Fly   392 SKTSNTSLP 400
            .:.|:  ||
Frog   527 DECSD--LP 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	84/315 (27%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	83/313 (27%)
wee2	NP_001096499.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..86
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..181
		PKc_like	216..486	CDD:389743	81/309 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910