DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7236 and cdk14

DIOPT Version :9

Sequence 1:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_012819652.1	Gene:	cdk14 / 100125075	XenbaseID:	XB-GENE-943250	Length:	469	Species:	Xenopus tropicalis

Alignment Length:	339	Identity:	121/339 - (35%)
Similarity:	173/339 - (51%)	Gaps:	40/339 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVK--RFVESEDDPAIRKIALREIRLLKNLKHPN 108
            |.|.||||.:||||||..|||.:.:..|.|||:|  |..|.|..|.   .|:||..|||.|||.|
Frog   131 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPF---TAIREASLLKGLKHAN 192

  Fly   109 LVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDI 173
            :|.|.::...|..|.||||:....:...:::||.|......|...:|.|.|::|.|:...||||:
Frog   193 IVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLNPENVKLFLFQLLRGLSYIHQGHILHRDL 257

  Fly   174 KPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLF 237
            ||:|:|::..|::||.|||.||..| |...|::.|.|.|||.|::|:|.|.|.|.:|:|.:||:|
Frog   258 KPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTDYSTCLDMWGVGCIF 322

  Fly   238 AELVRGEALWPGRSDV-DQLYLIRKTLGDLLPRHIQIFGQNEYFKGI-TLPVPPTLEPLEDKMPA 300
            .|:::|.|.:||..|: |||..|...||.         ...|.:.|: :||        ..|:..
Frog   323 VEMIQGVAAFPGMKDIQDQLERIFLILGT---------PNEETWPGVHSLP--------HFKLER 370

  Fly   301 KSQQNPLTI--------------DFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSL 351
            .:|..|..:              |...|.|...|..|.|.:....|.||.|...:..||..::|:
Frog   371 FTQYGPKNLRQAWNKLSYVNHAEDLASKLLQCFPKNRLSAQAALNHDYFSDLPPRLWELSDMSSI 435

  Fly   352 -EAANLRQQQLASQ 364
             ...|::.|..|.:
Frog   436 FTVPNVKLQPEAGE 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	111/305 (36%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	110/303 (36%)
cdk14	XP_012819652.1	STKc_PFTAIRE1	129..431	CDD:143374	117/319 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910