Protein Alignment Hsp60C and CCT3

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_012520.1
• Gene: CCT3 / 853438
• SGDID: S000003551
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 574
• Identity: 125/574 - (21%)
• Similarity: 233/574 - (40%)
• Gaps: 93/574 - (16%)

  Fly    25 NYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDK 89
            |.:::...|.:.:...:.....:||.:...:|||....::....|...:|.||..:.:.|.:
Yeast     9 NASQERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDV--- 70

  Fly    90 FQNIGAKLVQDVANNTNEEAGDGTTTATVLA-RAIAKEGFEKISRGASPVEIRRGVMLAIETVKD 153
             .:..||.:.:::...:||.||||||..:|| ..:|:.....|.:...||.|.:.:..|:....:
Yeast    71 -AHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQALKKALTDALE 134

  Fly   154 NLRRLSRPVNTPEEICQVATISAN-GDKSVGNLISEAIKKVGRDGVITV-KD-GKTLCDE----- 210
            .::::|:||:...:......|.|: |.|.|.:. ||.:.::..|.|.|| || |:|:..|
Yeast   135 VIKQVSKPVDVENDAAMKKLIQASIGTKYVIHW-SEKMCELALDAVKTVRKDLGQTVEGEPNFEI 198

  Fly   211 ------------------LEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSI 257
                              ..|::|:..::..:.|......:..:|...|..|.:  ||.:|..:|
Yeast   199 DIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVLLDCPLEY--KKGESQTNI 261

  Fly   258 VPALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGG 322
              .:|......:.|.|..|.::......|.|....|      :...|..|..:..|:     .||
Yeast   262 --EIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLV------ITEKGVSDLAQHYLL-----KGG 313

  Fly   323 IVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYEK 387
            ...        |..:|.||..|:..|.              .|.:..|||.|:|:...:.....|
Yeast   314 CSV--------LRRVKKSDNNRIARVT--------------GATIVNRVEDLKESDVGTNCGLFK 356

  Fly   388 EKM--QERLARLSS-----GVALLRVGGSSDVEVSEKKDRVIDALNATR-AAVEEGIVPGGG--- 441
            .:|  .|..:.|.:     ...::..|||.|: ::|....:.||:...| ..:...:.||||
Yeast   357 VEMIGDEYFSFLDNCKEPKACTIMLRGGSKDI-LNEIDRNLQDAMAVARNVMLSPSLSPGGGATE 420

  Fly   442 -TALLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCL--TIAKNAGVDGAMVVAKVEI--LDGDY 501
             ...::..:|...|:|..:.....:     |..|.|:  |:.:|||.|...:::::..  ..|::
Yeast   421 MAVSVKLAEKAKQLEGIQQWPYQAV-----ADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQGNF 480

  Fly   502 --GYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEE 553
              |.|..||:..:|:..||.:|..:.:.::..|...|.||...:.:|:.:..:|
Yeast   481 TTGIDGDKGKIVDMVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGVRKQE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	123/564 (22%)
CCT3	NP_012520.1	chap_CCT_gamma	4..533	CDD:274085	124/571 (22%)