Protein Alignment Hsp60C and TCP1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_010498.1
• Gene: TCP1 / 851798
• SGDID: S000002620
• Length: 559
• Species: Saccharomyces cerevisiae
• Alignment Length: 596
• Identity: 137/596 - (22%)
• Similarity: 240/596 - (40%)
• Gaps: 151/596 - (25%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |.::|...:.....:|:.|..::||.|.:.::....|...:|.||.|:   ::|.| .|:...|:
Yeast    22 GDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIGDFTVTNDGATI---LSLLD-VQHPAGKI 82

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAI-ETVKDNLRRLSRP 161
            :.::|...:.|.|||||:..::|..:.|...|.:.....|..|..|..:|: |.::.....||..
Yeast    83 LVELAQQQDREIGDGTTSVVIIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSTS 147

  Fly   162 VNT--PEEICQVATISANGDKSVG-------NLISE---AIKKVGRDGVI--TVK-------DGK 205
            |:|  .|.:..:|..|.: .|.:|       |::.:   |:|.....|.|  .||       .||
Yeast   148 VDTLGKETLINIAKTSMS-SKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKAVNVLKAHGK 211

  Fly   206 TLCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKP 270
            :..:.| ::.|          |.:|.:..::.         ..|:|......:..|:| |.|:..
Yeast   212 SATESL-LVPG----------YALNCTVASQA---------MPKRIAGGNVKIACLDL-NLQKAR 255

  Fly   271 LVI-----IAEDLEAEAL----STLVVNRLK----VGLQV----------CA---VKAPGFGDNR 309
            :.:     |.:..:.|.:    :.:|:.|:|    .|.||          |.   |:|...|..|
Yeast   256 MAMGVQINIDDPEQLEQIRKREAGIVLERVKKIIDAGAQVVLTTKGIDDLCLKEFVEAKIMGVRR 320

  Fly   310 --KENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSK---DDTMLLKGKGQKAEVEK 369
              ||:|..:|.|||..:....:|:...|..:.|..|...|||.:|   |:.:|:||
Yeast   321 CKKEDLRRIARATGATLVSSMSNLEGEETFESSYLGLCDEVVQAKFSDDECILIKG--------- 376

  Fly   370 RVEGLREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEE 434
                        ||.:            ||...:||  |::|..:.|.:..:.|:|:..:..:|.
Yeast   377 ------------TSKH------------SSSSIILR--GANDYSLDEMERSLHDSLSVVKRTLES 415

  Fly   435 G-IVPGGGTALLRCIQKL------NDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVA 492
            | :|||||     |::..      |........:.:.|.....||.:...|:|.||..|.:.:||
Yeast   416 GNVVPGGG-----CVEAALNIYLDNFATTVGSREQLAIAEFAAALLIIPKTLAVNAAKDSSELVA 475

  Fly   493 KVEILDG----------------DYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTT 541
            |:.....                :||.|.::|:..:.|..|:::||         .:.|.||.:.
Yeast   476 KLRSYHAASQMAKPEDVKRRSYRNYGLDLIRGKIVDEIHAGVLEPT---------ISKVKSLKSA 531

  Fly   542 AEAVVTELPLE 552
            .||.|..|.::
Yeast   532 LEACVAILRID 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	136/590 (23%)
TCP1	NP_010498.1	TCP1_alpha	17..549	CDD:239451	137/596 (23%)