Protein Alignment Hsp60C and CCT4

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_010138.1
• Gene: CCT4 / 851412
• SGDID: S000002302
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 595
• Identity: 134/595 - (22%)
• Similarity: 234/595 - (39%)
• Gaps: 162/595 - (27%)

  Fly    35 EVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKLVQ 99
            |||...:.....:|||:..::||||.:.:|:.|.|...|:.||.|:.|.:|:....    |:::.
Yeast    19 EVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAILHPV----ARMLV 79

  Fly   100 DVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEI--------RRGVMLAIE-----TV 151
            :|:...:.|||||||:..:|..|:.......:::|..|..|        :|.|.:.:|     ::
Yeast    80 EVSAAQDSEAGDGTTSVVILTGALLGAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSL 144

  Fly   152 KDNLRRLSRPVNT---------------PEEICQVATISANGDKSVGNLISEAIKKVGRDGVITV 201
            .|. .:|.|..:|               |..:..|..||....|:|.......:||||  |.|
Yeast   145 SDR-EQLVRAASTSLSSKIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKKVG--GTI-- 204

  Fly   202 KDGKTLCDELEVIEGMKFDRGYI----SPYFINTSKGAKVEFQDA-------------------- 242
                   |:.|:|:|:...:..|    .|.....:|...::||.:
Yeast   205 -------DDTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVNDYRQMDK 262

  Fly   243 --------LLLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCA 299
                    ||..| ||||.|...|             ::|.:.:..:|::.|.::.|. .|.:..
Yeast   263 ILKEERAYLLNIC-KKIKKAKCNV-------------LLIQKSILRDAVNDLALHFLS-KLNIMV 312

  Fly   300 VKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQK 364
            ||     |..:|.:..::...|         ...:.||::....|:|    |.|....:...|.|
Yeast   313 VK-----DIEREEIEFLSKGLG---------CKPIADIELFTEDRLG----SADLVEEIDSDGSK 359

  Fly   365 AEVEKRVEGLREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATR 429
            .   .||.|:|......|.|                   :.:.|::::.:.|.:..:.|||...|
Yeast   360 I---VRVTGIRNNNARPTVS-------------------VVIRGANNMIIDETERSLHDALCVIR 402

  Fly   430 AAVEE-GIVPGGGTALLRCIQKLNDLKGANEDQNM-GIEI-----IRRALRMPCLTIAKNAGVDG 487
            ..|:| |::.|||...:...::|     :.|.::| |::.     ...||.:...|:|:|||::.
Yeast   403 CLVKERGLIAGGGAPEIEISRRL-----SKEARSMEGVQAFIWQEFASALEVIPTTLAENAGLNS 462

  Fly   488 AMVVAKV-------EILDGDYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAV 545
            ..||.::       |:.|   |....:....|..|..|:.|..|..:||:.|         :|.|
Yeast   463 IKVVTELRSKHENGELND---GISVRRSGTTNTYEEHILQPVLVSTSAITLA---------SECV 515

  Fly   546 VTELPLEEAA 555
            .:.|.:::.|
Yeast   516 KSILRIDDIA 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	132/586 (23%)
CCT4	NP_010138.1	chap_CCT_delta	11..528	CDD:274083	134/595 (23%)