Protein Alignment Hsp60C and Hsp60B

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 345/583 - (59%)
• Similarity: 443/583 - (75%)
• Gaps: 31/583 - (5%)

  Fly    22 WARNYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIAL 86
            :||.|:||||||..|||||::|||:||||||||||||||:||:|:.|.||||||||.|||:||||
  Fly    16 FARMYSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIAL 80

  Fly    87 KDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETV 151
            ||:..|:|||||||||:||||.||||||||||||||||||||.:|:.||:|||||||||||::.|
  Fly    81 KDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVV 145

  Fly   152 KDNLRRLSRPVNTPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVKDGKTLCDELEVIEG 216
            ||.|:.:|:.|.|.|||.||||:|||||..:|.||.||..|||..|.|||||||.|.|||.:|:|
  Fly   146 KDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQG 210

  Fly   217 MKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAE 281
            ::||.||:||:|:|:|||:||||.:||::...|||.....||..||.:..||:||:|||||:..|
  Fly   211 LRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGE 275

  Fly   282 ALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVG 346
            ||:.||:|:|::||||||||:|.:|.:|||.:.|::.|||..:|||:.|..::|:.|:.|.|:||
  Fly   276 ALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVG 340

  Fly   347 EVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYE-KEKMQERLARLSSGVALLRVGGSS 410
            |.|:|||.||||:||.:...:|.|::.:::.:.|.....| ::::::||:.|:.|||:|.:||.|
  Fly   341 EAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGS 405

  Fly   411 DVEVSEKKDRVIDALNATRAAVEEGIVPGGGTALLRCIQKLNDLKGANEDQNMGIEIIRRALRMP 475
            :|||:||||||:|||||||||:|||||||||||.||||..|.:||..:.|...|::|:..|||||
  Fly   406 EVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELKTESADLQKGVDIVCNALRMP 470

  Fly   476 CLTIAKNAGVDGAMVVAKVEILDG--DYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASL 538
            |.|||:||||||.||||||  |:|  ||||||:..||..::|:||||||||:||||:||||||||
  Fly   471 CQTIAQNAGVDGPMVVAKV--LNGSEDYGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASL 533

  Fly   539 LTTAEAVVTEL-------------------------PLEEAAAAGAAAGLGALGGM-GMGGMG 575
            |:|.|.|:|:.                         .|||.||.....|:|.:||| ||||||
  Fly   534 LSTTEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGMGGMGGMGGMGGMG 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	325/522 (62%)
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	325/522 (62%)