Protein Alignment Hsp60C and CCT8

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_610418.1
• Gene: CCT8 / 35882
• FlyBaseID: FBgn0284436
• Length: 546
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 137/622 - (22%)
• Similarity: 232/622 - (37%)
• Gaps: 168/622 - (27%)

  Fly    27 AKDVRFGPEVRAMMLQGVDV---LADAV----------AVTM----GPKGRNVIIEQSWGSPKIT 74
            |..|...|.|..|:..|..:   |.:||          |.||    ||.|.|.:|........:|
  Fly     2 ALSVPKAPGVSQMLKDGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVT 66

  Fly    75 KDGVTVAKSIALKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVE 139
            .|..|:.:.:.:    ::..|||:...:...:.|.||||....|||.|:.:...|.:..|.:..|
  Fly    67 SDAGTIMRELDV----EHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAE 127

  Fly   140 IRRGVMLAIETVKDNLRRL-------SRPVNTPEEICQVATISAN-GDKS-VGNLISEAIKKVGR 195
            |..|...|:|...:.|..|       .|.|...:|:.:.:.:|.. |.:. :.:|:|:|...:..
  Fly   128 ISDGYEKALEKALEILPNLVSHKIEDYRNVEKVKEVLRTSIMSKQYGQEDFLNDLVSKACVSILP 192

  Fly   196 D-GVITVKDGKTLCDEL-------EVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKK-- 250
            | |...| |...:|..|       ||:.||.|.|                 |.:..:.:.||.
  Fly   193 DEGTFNV-DNIRICKILGSGLTKSEVVRGMVFKR-----------------FVEGDVTYAEKAKI 239

  Fly   251 -IKSAPSIVPALELANAQRKPLVII--AEDL------EAEALSTLVVNRLKVGLQVCAVKAPGFG 306
             |.|.|     :::...:.|..|:|  |::|      |...|.:.:......|::|
  Fly   240 VIFSCP-----VDIIQTETKGTVLIKSADELLSFSSGEESLLESQIKAIADAGVKV--------- 290

  Fly   307 DNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRV 371
                       |..||.| ||.|...      ::.:|.:...:.||.|...| .:...|.|..|:
  Fly   291 -----------VVAGGKV-GDMALHF------LNKYGLMAVRLNSKFDLRRL-SRSVNATVLPRI 336

  Fly   372 EGLREAIKESTSSYEK---------EKMQE------RLARLSSGVALLRVGGSSDVEVSEKKDRV 421
                     :|.|.|:         |::.:      |.....|.:|.:.:.|::|..:.:.:..:
  Fly   337 ---------TTPSQEELGYCDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGATDNFMDDIERAL 392

  Fly   422 IDALNATRAAVEEG-IVPGGGTALLRCIQKLNDLKGANEDQNMGIE--IIRR---ALRMPCLTIA 480
            .||:|..:....:| .:||.|...:....:|:    |..|...|::  .:|:   ||.:....:|
  Fly   393 DDAINNFKCLTRDGRYLPGAGATEIELATQLS----AYADTLPGLDQYAVRKFANALEVFPKALA 453

  Fly   481 KNAGVDGAMVVAKVEILDGDYGYDALKGEYGNMI-------ERGIIDPTKVVR--------TAIS 530
            :|:|::|..:|.::        |.|...|.|..|       :...||.||...        ..:.
  Fly   454 ENSGINGTEIVNQL--------YLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFWGLK 510

  Fly   531 DAAGVASLLTTAEAVVTELPLEEAAAAGA-----AAG 562
            .|.|.|:.:...:.::.      |..||.     |||
  Fly   511 YAVGAAATILKVDQIIM------AKRAGGPKVRQAAG 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	130/600 (22%)
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	125/590 (21%)